RNA: Folding into Function
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Structure and Dynamics".
Deadline for manuscript submissions: closed (1 December 2019) | Viewed by 3219
Special Issue Editor
Interests: bioinformatics; biochemistry; biology; RNA
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
All biological processes involve or are influenced by RNA, and all RNA biology involves or is influenced by RNA folding. This can involve specific intramolecular RNA secondary/tertiary structures that recognize regulatory factors, or non-specific “structuredness” that can affect the accessibility or relative location of RNA regulatory elements. Likewise, RNA intermolecular interactions (with other RNAs, DNAs or proteins) play critical roles in biology—this can also be affected by intramolecular folding within the interacting RNA molecule(s). The challenges of attaining knowledge about RNA folding into function are currently occupying a multitude of researchers across a wide array of disciplines, including bioinformatics, biochemistry, biophysics and molecular/cell biology. The complexity of this topic necessitates integrative multidisciplinary approaches, and the goal of this Special Issue of Biomolecules is to bring together contributions from top researchers in the field to provide a broad perspective and help draw connections between disparate knowledge domains. Submissions will include reviews of cutting-edge methods for predicting/determining RNA secondary and tertiary structure/dynamics and intermolecular interactions, as well as reviews of how RNA folding has informed our understanding of its function across a broad range of targets: spanning viruses/viroids, microorganisms, fungi, plants, and animals.
Dr. Walter Moss
Guest Editor
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Keywords
- RNA
- structure
- prediction
- noncoding RNA
- folding
- posttranscriptional control
- gene expression
- regulation
- motif discovery
- sequence analysis
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