Interplay between Viral Infections and Metabolic and Redox Pathway
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 2815
Special Issue Editor
Interests: hepatitis virus; SARS-CoV-2; influenza virus; metabolomics; polyamines; antiviral agents
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cell metabolism is tightly linked with proliferation, differentiation and functioning. The development of various pathologies, including cancer, autoimmune diseases, and endocrine diseases, is associated with the alteration of metabolic pathways. Inhibitors of metabolic enzymes and metabolite transporters can be used for their treatment, as exemplified by a wide array of drugs such as statins, metformin, sulfasalazine, methotrexate, and eflornithine.
Reactive oxygen species (ROS) comprise a group of oxygen intermediates generated in different cell compartments. Their overproduction is associated with the development of various pathologies. ROS modulate signaling pathways, as they can specifically target the cysteine residues of certain proteins, affecting their activity. Changes in cellular redox status are tightly linked to the dysregulation of metabolic pathways.
Viral infections interfere with various metabolic and redox pathways of host cells. In the current Special issue, we would like to bring together research papers and reviews on an interplay between viral infections and metabolic and redox pathways. The topics include but are not limited to:
- Alteration of redox and metabolic pathways in infected cells;
- Role of ROS and metabolic pathways in virus replication;
- Role of changes in redox and metabolic pathways in virus pathogenesis;
- Potential activity of antioxidants and inhibitors of metabolic enzymes as antiviral agents or drugs to treat virus-associated diseases;
- Redox biology and metabolism studies of non-communicable diseases, elements of which can be used in virology.
Dr. Alexander Ivanov
Guest Editor
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Keywords
- metabolism
- reactive oxygen species
- antiviral agents
- replication
- virus
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