State-of-the-Art in Antibiotics Resistance
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 7955
Special Issue Editor
2. Research Centre for Natural Sciences, Institute of Materials and Environmental Chemistry, 1113 Budapest, Hungary
Interests: dNTP metabolism; enzyme kinetics; nucleotide hydrolases; motor proteins; genome instability; DNA repair; mycobacterial genetics; antibiotics resistance
Special Issue Information
Dear Colleagues,
This Special Issue is dedicated to revisiting the status of research dealing with any molecular aspects of antibiotic resistance.
The widespread use of antibiotics in the 1940s was one of the greatest achievements in medicine. Along with vaccination, it was probably the most efficient factor in human history to reduce mortality and increase life expectancy. Since then, antibiotics have been used successfully to treat diseases that were previously thought to be fatal. However, shortly after the start of the use of antibiotics, it became clear that antibiotic resistance is inherently coupled with antibiotic use and that its onset is accelerated by the misuse and overuse of antibiotic substances. Antibiotic resistance typically emerges within some years of the deployment of a novel antibiotic. Today, we face the worldwide challenge of hardly treatable or practically untreatable bacterial infections caused by multidrug resistant strains. Meanwhile, the appearance of new antibiotics in the pharmaceutical market has slowed down. Therefore, ingenious action against resistance is likely to be key to mitigate the threat from microbial diseases. In this thematic collection, original manuscripts and reviews addressing the molecular mechanisms of the emergence of antibiotic resistance, as well as new concepts to circumvent it, are welcome.
Dr. Judit Toth
Guest Editor
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Keywords
- antibiotic resistance
- antimicrobial resistance
- multidrug resistance
- extreme drug resistance
- drug tolerance
- bacterial infections
- antibacterial treatment
- antibiotic treatment strategy
- infection control
- resistome
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