The Application of Biomaterials in Electronics and Biosensors

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 1469

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School of Integrative Engineering, Chung-Ang University, Seoul 06974, Republic of Korea
Interests: sensor; biosensor; fiber sensor; e textile; conductive textile
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Special Issue Information

Dear Colleagues,

This Special Issue on "The Application of Biomaterials in Electronics and Biosensors" aims to explore the innovative integration of biomaterials in the development of electronic devices and biosensors, highlighting advances that leverage biological materials for enhanced performance, biocompatibility, and sustainability. Biomaterials, including polymers, peptides, and biologically derived molecules, have shown remarkable potential in creating electronic components that are flexible, efficient, and capable of interfacing with biological environments. This issue will cover a range of topics from the synthesis and characterization of biomaterials and their application in electronic circuits and sensor design, to their roles in wearable technology, health monitoring, and environmental sensing. Emphasis will be placed on cutting-edge research that showcases the versatility of biomaterials in electronics and biosensor technology, offering insights into novel fabrication techniques, material properties, and application-specific design considerations. Through this Special Issue, we aim to highlight the pivotal role of biomaterials in shaping the future of electronics and sensor technology, fostering interdisciplinary collaboration and innovation.

Dr. Byungil Hwang
Guest Editor

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Keywords

  • biomaterials
  • electronics
  • biosensors
  • biocompatibility
  • sustainable technology
  • wearable technology
  • health monitoring
  • environmental sensing
  • fabrication techniques
  • interdisciplinary research

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Published Papers (2 papers)

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Research

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15 pages, 2864 KB  
Article
Rapid Detection of Staphylococcus aureus in Milk Samples by DNA Nanodendrimer-Based Fluorescent Biosensor
by Mukaddas Mijit, Dongxia Pan, Hui Wang, Chaoqun Sun and Liang Yang
Biosensors 2025, 15(8), 527; https://doi.org/10.3390/bios15080527 - 12 Aug 2025
Viewed by 367
Abstract
Staphylococcus aureus is the primary pathogen responsible for mastitis in dairy cows and foodborne illnesses, posing a significant threat to public health and food safety. Here, we developed an enhanced sensor based on solid-phase separation using gold-magnetic nanoparticles (Au@Fe3O4) [...] Read more.
Staphylococcus aureus is the primary pathogen responsible for mastitis in dairy cows and foodborne illnesses, posing a significant threat to public health and food safety. Here, we developed an enhanced sensor based on solid-phase separation using gold-magnetic nanoparticles (Au@Fe3O4) and signal amplification via dendritic DNA nanostructures. The substrate chain was specifically immobilized using thiol–gold coordination, and a three-dimensional dendritic structure was constructed through sequential hybridization of DNAzymes, L chains, and Y chains, resulting in a 2.8-fold increase in initial fluorescence intensity. Upon specific cleavage of the substrate chain at the rA site by S. aureus DNA, the complex dissociates, resulting in fluorescence intensity decay. The fluorescence intensity is negatively correlated with the concentration of Staphylococcus aureus. After optimization, the biosensor maintains a detection limit of 1 CFU/mL within 3 min, with a linear range extended to 1–107 CFU/mL (R2 = 0.998) and recovery rates of 85.6–102.1%, significantly enhancing resistance to matrix interference. This provides an innovative solution for rapid on-site detection of foodborne pathogens. Full article
(This article belongs to the Special Issue The Application of Biomaterials in Electronics and Biosensors)
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Review

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14 pages, 1452 KB  
Review
Recent Advances in Liquid Metal-Based Stretchable and Conductive Composites for Wearable Sensor Applications
by Boo Young Kim, Wan Yusmawati Wan Yusoff, Paolo Matteini, Peter Baumli and Byungil Hwang
Biosensors 2025, 15(7), 466; https://doi.org/10.3390/bios15070466 - 19 Jul 2025
Viewed by 721
Abstract
Liquid metals (LMs), with their unique combination of high electrical conductivity and mechanical deformability, have emerged as promising materials for stretchable electronics and biointerfaces. However, the practical application of bulk LMs in wearable sensors has been hindered by processing challenges and low stability. [...] Read more.
Liquid metals (LMs), with their unique combination of high electrical conductivity and mechanical deformability, have emerged as promising materials for stretchable electronics and biointerfaces. However, the practical application of bulk LMs in wearable sensors has been hindered by processing challenges and low stability. To overcome these limitations, liquid metal particles (LMPs) encapsulated by native oxide shells have gained attention as versatile and stable fillers for stretchable and conductive composites. Recent advances have focused on the development of LM-based hybrid composites that combine LMPs with metal, carbon, or polymeric fillers. These systems offer enhanced electrical and mechanical properties and can form conductive networks without the need for additional sintering processes. They also impart composites with multiple functions such as self-healing, electromagnetic interference shielding, and recyclability. Hence, the present review summarizes the fabrication methods and functional properties of LM-based composites, with a particular focus on their applications in wearable sensing. In addition, recent developments in the use of LM composites for physical motion monitoring (e.g., strain and pressure sensing) and electrophysiological signal recording (e.g., EMG and ECG) are presented, and the key challenges and opportunities for next-generation wearable platforms are discussed. Full article
(This article belongs to the Special Issue The Application of Biomaterials in Electronics and Biosensors)
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