Advances in Flexible Bioelectronics and Intelligent Biosensing Systems - 2nd Edition

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Nano- and Micro-Technologies in Biosensors".

Deadline for manuscript submissions: 20 July 2026 | Viewed by 614

Special Issue Editor


E-Mail Website
Guest Editor
Institute of Medical Equipment Science and Engineering, Huazhong University of Science and Technology, Wuhan, China
Interests: flexible functional materials; bio-interfaced electronics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are excited to announce the launch of the second volume of our Special Issue titled “Advances in Flexible Bioelectronics and Intelligent Biosensing Systems –2nd Edition”. Building upon the success of our first edition, this Special Issue aims to further explore the rapidly evolving field of flexible bioelectronics and intelligent biosensing technologies.

Flexible bioelectronics and intelligent biosensing systems continue to revolutionize the way we monitor and interpret biophysiological signals. The integration of these advanced technologies not only enhances long-term health monitoring and early disease diagnosis but also paves the way for proactive lifestyle and disease management strategies. As demand grows for high-quality, flexible solutions that are robust, conformable, user-friendly, and clinically informative, sharing the latest advancements in this dynamic field becomes essential.

The second edition encompasses a more diverse range of topics, including but not limited to:

  1. Innovative designs and materials for flexible bioelectronics;
  2. Development of AI- and ML-enabled biosensors for disease diagnosis;
  3. Intelligent sensing systems and their applications;
  4. Integration of flexible electronics with wearable technology;
  5. Clinical applications and case studies in bioelectronic devices;

We are looking forward to your contributions that will inspire further research and innovation in this area of biosensing.

Dr. Shuwen Chen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioelectronics
  • biosensors
  • flexible sensors
  • flexible electronics
  • wearable sensors
  • healthcare electronics
  • biomedical electronics
  • biochemical sensors
  • bio-interfaced physical sensors
  • artificial intelligence

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

21 pages, 1655 KB  
Article
Capacitive Biosensing of Skin Irritants Using a Lanolin-Based Artificial Stratum Corneum Model
by Chung-Ting Cheng, Yi Kung, Hung-Yu Chen, Kuang-Hua Chang, Richie L. C. Chen and Tzong-Jih Cheng
Biosensors 2025, 15(9), 564; https://doi.org/10.3390/bios15090564 - 28 Aug 2025
Viewed by 535
Abstract
Skin irritation testing is transitioning toward non-animal alternatives that can replicate the functional properties of the human stratum corneum (SC). To address this need, we report a capacitive biosensing platform that integrates a lanolin-based artificial SC (aSC) for rapid, indicator-free detection of chemical [...] Read more.
Skin irritation testing is transitioning toward non-animal alternatives that can replicate the functional properties of the human stratum corneum (SC). To address this need, we report a capacitive biosensing platform that integrates a lanolin-based artificial SC (aSC) for rapid, indicator-free detection of chemical irritants. The approach leverages a membrane-bound lipid matrix to detect changes in interfacial capacitance caused by chemical exposure. Among candidate materials, lanolin emerged as the most effective SC mimic, showing reproducible baseline stability and responsive dielectric shifts. The system quantifies barrier integrity through the capacitance change rate (ΔC/Δt), which serves as a real-time indicator of irritation potential. By positioning the biosensor as an analog of the SC and monitoring the dielectric environment during short exposures (7.5 min), we shift the paradigm from endpoint-based biochemical assays to rapid, physicochemical screening. This concept supports the advancement of ethical, scalable testing platforms that reduce reliance on animal or cellular models while maintaining sensitivity to barrier-compromising agents. Full article
Show Figures

Graphical abstract

Back to TopTop