Surface Plasmon Resonance (SPR)-Based Sensors
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Optical and Photonic Biosensors".
Deadline for manuscript submissions: closed (30 July 2021) | Viewed by 15844
Special Issue Editor
Interests: ribozymes; RNA-protein interactions; 3D structures of RNA-protein complexes; aptamers; aptamer-based biosensors; molecular beacon aptamers; anti-viral aptamers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Surface Plasmon Resonance (SPR) has been used to analyze a wide range of biomolecular interactions, including protein–protein, DNA–protein, RNA–protein, antigen–antibody, lipid membrane–protein, protein–glycan or polysaccharide, protein–small ligand, DNA–small ligand, RNA–small ligand, receptor–drug, and receptor–virus interactions. SPR enables label-free detection, which makes it possible to monitor complexes in a real-time fashion, and facilitates the isolation of complexes if necessary. SPR-based biomolecular analyses require only a small amount of sample to characterize the binding efficiency between the two ligands for the purpose of determining the rate constants. Although the analysis of biomolecular interactions is carried out routinely using SPR in batch mode, in recent years most biomolecular analyses have been routinely carried out in a high-throughput fashion that includes drug discovery.
Considering the recent developments in SPR applications, we plan to publish a Special Issue entitled “Surface Plasmon Resonance (SPR)-Based Sensors”. For this Special Issue, we invite authors to submit manuscripts that help to advance SPR methods and applications in various fields, including drug discovery, quality analysis, evaluation of macromolecular interactions, and high-throughput analyses of biomolecular interactions.
Dr. Penmetcha Kumar
Guest Editor
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Keywords
- SPR
- biomolecular interactions
- drug discovery
- diagnosis
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