Fluorescent Biosensors: New Methods, Devices and Important Applications

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Optical and Photonic Biosensors".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 1025

Special Issue Editors


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Guest Editor
National Reference Lab for Agricultural Testing (Biotoxin), Key Lab of Detection for Mycotoxin, Ministry of Agriculture and Rural Affairs PRC, Lab of Quality & Safety Risk Assessment for Oilseeds Products (Wuhan), Ministry of Agriculture and Rural Affairs PRC, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China
Interests: fluorescence immunosensor; functional biomaterials and nanomaterials for capture; analysis; diagnosis; warning; prevention of and reduction in toxins
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Novaptech, 33600 Pessac, France
Interests: aptamer; synthetic oligonucleotide; aptasensor; fluorescence detection; light-up aptamer; molecular beacon; SPR

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Guest Editor
National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba 305-0044, Japan
Interests: fluorescence enhancement; nanostructure-based biosensors; metasurfaces; metamaterials; nanophotonics; plasmonics

Special Issue Information

Dear Colleagues,

Fluorescence is a type of important signal in biosensors, which is usually highly sensitive. It has been paid significant attention in biotracing (e.g., intracellular protein interaction or location), diagnosis (e.g., pathogen diagnosis for human, livestock, and crops), analytical chemistry (e.g., detection contaminant/chemical in food or environmental samples), and other fields. Fluorescent materials include organic compounds, proteins, inorganic fluorescent materials, etc. Resonance fluorescence, polarization fluorescence, time-resolved fluorescence, and other methods have emerged. This Special Issue focuses on fluorescence biosensing, including (but not limited to) new methods, new devices, important new applications, etc. We invite researchers to share their work on fluorescent biosensors, and original research articles and comprehensive reviews will be considered for publication.

Prof. Dr. Qi Zhang
Dr. Jean Jacques Toulme
Dr. Masanobu Iwanaga
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • fluorescence
  • biosensor
  • method
  • device
  • application
  • food
  • agriculture
  • environment
  • pathogen
  • contaminant

Published Papers (1 paper)

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Review

31 pages, 3609 KiB  
Review
Fluorogenic RNA-Based Biosensors of Small Molecules: Current Developments, Uses, and Perspectives
by Janine Kehrli, Claire Husser and Michael Ryckelynck
Biosensors 2024, 14(8), 376; https://doi.org/10.3390/bios14080376 - 1 Aug 2024
Viewed by 476
Abstract
Small molecules are highly relevant targets for detection and quantification. They are also used to diagnose and monitor the progression of disease and infectious processes and track the presence of contaminants. Fluorogenic RNA-based biosensors (FRBs) represent an appealing solution to the problem of [...] Read more.
Small molecules are highly relevant targets for detection and quantification. They are also used to diagnose and monitor the progression of disease and infectious processes and track the presence of contaminants. Fluorogenic RNA-based biosensors (FRBs) represent an appealing solution to the problem of detecting these targets. They combine the portability of molecular systems with the sensitivity and multiplexing capacity of fluorescence, as well as the exquisite ligand selectivity of RNA aptamers. In this review, we first present the different sensing and reporting aptamer modules currently available to design an FRB, together with the main methodologies used to discover modules with new specificities. We next introduce and discuss how both modules can be functionally connected prior to exploring the main applications for which FRB have been used. Finally, we conclude by discussing how using alternative nucleotide chemistries may improve FRB properties and further widen their application scope. Full article
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