Advanced Smart-Biomaterials for Biosensing, Diagnostic and Tissue Engineering

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor Materials".

Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 2343

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The Engineering-Meets-Medicine Laboratory, Stony Brook University, Stony Brook, NY 11794, USA
Interests: biodegradable metals; surface coatings and functionalizations; immunomodulation; bioresorbable implants
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Special Issue Information

Dear Colleagues,

Biomaterials, both natural and synthetic, living and nonliving, interact with biological systems for a medical purpose. In medicine, these biomaterials can augment or replace various natural functions, and be applied for diagnostic and therapeutic treatments. In addition to allowing a biomaterial to be biocompatible, biofunctions have various other applications. Smart biomaterials possessing unique physical, chemical, or biological properties have been developed in recent decades to realize instructive/inductive functions in biomaterial–tissue inteactions and tissue engineering. This also provides opportunities to engineer different materials and electrical and sensing components with specific and unique advantages for smart biomaterial systems. This Special Issue aims to present the latest works on the development and various applications of smart biomaterials, collect the most recent development and findings, further explore smart biomaterial systems and clinical applications, and provide perspectives on the future direction of this field.

Dr. Yingchao Su
Guest Editor

Manuscript Submission Information

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Published Papers (1 paper)

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Review

21 pages, 10089 KiB  
Review
Rational Fabrication of Ionic Covalent Organic Frameworks for Chemical Analysis Applications
by Jing Yu, Liuna Luo, Hong Shang and Bing Sun
Biosensors 2023, 13(6), 636; https://doi.org/10.3390/bios13060636 - 8 Jun 2023
Cited by 2 | Viewed by 1873
Abstract
The rapid development of advanced material science boosts novel chemical analytical technologies for effective pretreatment and sensitive sensing applications in the fields of environmental monitoring, food security, biomedicines, and human health. Ionic covalent organic frameworks (iCOFs) emerge as a class of covalent organic [...] Read more.
The rapid development of advanced material science boosts novel chemical analytical technologies for effective pretreatment and sensitive sensing applications in the fields of environmental monitoring, food security, biomedicines, and human health. Ionic covalent organic frameworks (iCOFs) emerge as a class of covalent organic frameworks (COFs) with electrically charged frames or pores as well as predesigned molecular and topological structures, large specific surface area, high crystallinity, and good stability. Benefiting from the pore size interception effect, electrostatic interaction, ion exchange, and recognizing group load, iCOFs exhibit the promising ability to extract specific analytes and enrich trace substances from samples for accurate analysis. On the other hand, the stimuli response of iCOFs and their composites to electrochemical, electric, or photo-irradiating sources endows them as potential transducers for biosensing, environmental analysis, surroundings monitoring, etc. In this review, we summarized the typical construction of iCOFs and focused on their rational structure design for analytical extraction/enrichment and sensing applications in recent years. The important role of iCOFs in the chemical analysis was fully highlighted. Finally, the opportunities and challenges of iCOF-based analytical technologies were also discussed, which may be beneficial to provide a solid foundation for further design and application of iCOFs. Full article
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