Diagnosis, Treatment, and Prognosis of Neuromuscular Disorders
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neuromuscular and Movement Disorders".
Deadline for manuscript submissions: 30 May 2025 | Viewed by 2019
Special Issue Editors
Interests: neuromuscular disease; neuroimmunology; neurogenetics; myasthenia gravis; ATTRv amyloidosis; clinical neurophysiology
Special Issues, Collections and Topics in MDPI journals
Interests: neuromuscular disorders; electromiography/evoked potential; clinical neurophysiology; myasthenia gravis; music therapy; rare disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Background and History of this topic: Neuromuscular disorders (NMDs) comprise a large group of diseases affecting the peripheral nervous system, characterized by muscles, peripheral nerves, and neuromuscular junction. Progressive muscle weakness is the predominant condition in these disorders, often associated and depending on the specific involved system, with alterations in sensitivity, fatigue, and muscle atrophy, with a variable progression over time.
The diagnosis is often complex, as many of these are rare pathologies which require multidisciplinary support at dedicated centers, often representing a challenge for the clinician.
Good knowledge of the natural history of each NMD is essential in ensuring an optimal timing of the therapeutic interventions, which must be performed under the best possible conditions in these usually frail patients. Many of these disorders are treatable if the treatment is initiated early and appropriately. In recent decades, the prognosis of a wide spectrum of NMDs has significantly improved, thanks to the advent of new disease modify therapies. Several treatments have been employed, ranging from corticosteroids and intravenous immunoglobulins to immunosuppressive and targeted therapies, particularly in autoimmune NMDs like Myasthenia gravis and CIDP. Additionally, genetic enzymatic therapies have emerged for certain inherited metabolic myopathies, like Pompe disease. These diverse interventions underscore the necessity of a multidisciplinary approach in treatments.
Aim and Scope
To provide a comprehensive overview of recent developments in the diagnostic, prognostic, and therapeutic realms of NMDs.
Cutting-edge research: We welcome manuscripts focusing on the diagnosis and management of specific forms of neuromuscular diseases. Research exploring the necessity for novel diagnostic biomarkers, such as muscle magnetic resonance imaging and nerve ultrasound, is of particular interest. Additionally, studies investigating immunomodulatory therapies, including monoclonal antibodies, and the role of physical and cognitive rehabilitation in patient care are encouraged. Rare and complex clinical cases that shed light on unique challenges and treatment strategies are also valued contributions.
What kind of papers we are soliciting: Original articles, systematic reviews, and case reports that advance our understanding and management of neuromuscular disorders.
Dr. Vincenzo Di Stefano
Dr. Claudia Vinciguerra
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neuromuscular disorders
- neurogenetics
- neuroimmunology
- polyneuropathy
- myopathy
- neuromuscular junction disease
- diagnosis
- prognosis
- treatment
- rehabilitation
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