Etiology, Symptoms and Treatment of Epilepsy
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurodegenerative Diseases".
Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 15971
Special Issue Editors
Interests: epilepsy; therapeutics; neurodegenerative disorders; neurobiology of obesity; sleep; spinal cord injury; sleep technology; digital health; democratizing health for all
Interests: amyotrophic lateral sclerosis; epilepsy; developmental origins of health and disease (DOHaD); vitamin B12; sleep; spinal cord injury; therapeutics; digital health; maternal and child health; nutrition
Special Issue Information
Dear Colleagues,
Epilepsy is a common neurological disorder marked with episodes of seizures. These seizures are accompanied by muscle stiffness, loss of awareness, anxiety, fear, confusion, problems breathing and jerking of the legs and arms. A seizure can either be focal or generalized, depending upon the region of brain exhibiting the abnormal activity. For unknown reasons, the incidence of epilepsy is higher in low-income countries than in high-income countries. Head injuries, brain infections, vascular diseases and gene abnormalities are common factors responsible for the development of epilepsy. Families with rare autosomal dominant monogenic epilepsy have more than 30 distinct mutated genes. Many epilepsy-associated mutations have been reported in non-ion channel genes, such as genes for neural receptors, transcription factors and enzymes. The treatment of epilepsy includes antiepileptic drugs (AEDs) and surgery. If a patient responds poorly to AEDs, surgery is suggested; this includes deep brain stimulation, corpus callosotomy and resective surgery to lessen the symptoms or decrease the use of AEDs. The most common AEDs include lamotrigine, topiramate, sodium valproate and levetiracetam. This Special Issue focuses on (but is not limited to) the symptoms of epilepsy, its etiology, new intervention methods involved in its treatment and future research directions.
Dr. Jitendra Kumar Sinha
Dr. Shampa Ghosh
Guest Editors
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Keywords
- seizures
- therapeutics
- pediatric and adult types
- EEG
- TMS
- non-invasive brain stimulation
- epilepsy surgery
- ethnopharmacology
- cognition
- depression
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