Novel Targets and Therapies for Motor Neuron Diseases
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Molecular and Cellular Neuroscience".
Deadline for manuscript submissions: closed (30 September 2019) | Viewed by 5351
Special Issue Editor
Interests: neurodegeneration; ALS; neurotrauma; neural regeneration
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Motor neuron diseases (MND) collectively cause progressive loss of motor control to muscles of the body, instigating a range of symptoms including paralysis of the limbs, speech difficulties (dysphonia), swallowing dysfunction (dysphagia) and respiratory failure. Several forms of MND have been classified, and the most common and well known is amyotrophic lateral sclerosis (ALS). Some MND have a genetic component and are hereditary, though many cases are sporadic and the cause is unknown. Various cell types and structures in both the central nervous system and periphery contribute to the course of disease progression, and once diagnosed the disease has often reached advanced stages. Though the need is critical, there are no cures for MND, and available treatments are limited. As such, understanding disease progression before and beyond symptom onset, and identifying and developing novel therapies to delay or halt progression and extend lifespan are of great importance. This Special Issue is dedicated to highlighting exciting research into novel therapeutics which may have positive effects on MND at different stages of disease progression with the ultimate goal of identifying truly effective treatments for translation to clinical application.
Dr. Chandler L. Walker
Guest Editor
Manuscript Submission Information
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Keywords
- neurodegeneration
- ALS
- neurotrauma
- neural regeneration
