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Brain Sciences, Volume 15, Issue 10

October 2025 - 106 articles

Cover Story: Mobile typing, a ubiquitous and complex motor activity, offers a window into human sensorimotor and cognitive processes, as the rapid evolution of digital environments necessitates continuous adaptation to new platforms and tasks. This narrative review examines skill acquisition and adjustment to mobile interfaces, various typing modalities, and methodological approaches to studying touchscreen interactions. It evaluates the emerging potential of mobile typing as a source of novel, non-invasive behavioral biomarkers for monitoring brain health, aging, neurological conditions, and affective states. The paper also identifies key theoretical and empirical gaps, paving the way for future research to leverage mobile typing as a paradigm for advancing fundamental understanding of sensorimotor learning, development, and cognitive function. View this paper
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Articles (106)

  • Systematic Review
  • Open Access
519 Views
21 Pages

21 October 2025

Background/Objectives: Despite efforts, schizophrenia remains a difficult disease to treat for cognitive, positive, negative, and mood symptoms. In the present review, we explore existing data on the ameliorating effects of neurocognitive rehabilitat...

  • Review
  • Open Access
784 Views
29 Pages

Using Low-Intensity Focused Ultrasound to Treat Depression and Anxiety Disorders: A Review of Current Evidence

  • Ao Du,
  • Manli Huang,
  • Zheng Wang,
  • Hetong Zhou,
  • Huilong Duan,
  • Shaohua Hu and
  • Yinfei Zheng

21 October 2025

Background: Depression and anxiety disorders impact millions globally. In recent years, low-intensity focused ultrasound (LIFU), characterized by its high precision, deep penetration, and non-invasive nature, has garnered significant interest in neur...

  • Article
  • Open Access
370 Views
18 Pages

Neuropeptides, Altruism, and Adverse Childhood Experiences: Investigating Biological and Behavioral Correlations in Medical Students

  • Jennifer Khong,
  • Lauren Bennett,
  • Johanna Felix Rivera,
  • Nathan Andrews,
  • Veronica Vuong,
  • Demi Zapata,
  • Phillip Khong and
  • Rebecca Ryznar

21 October 2025

Background/Objectives: This pilot study aimed to investigate the relationship between salivary neuropeptides levels, adverse childhood experiences (ACEs), and altruism in a sample of medical students. Additionally, the study examined potential sex di...

  • Article
  • Open Access
291 Views
13 Pages

21 October 2025

Background/Objectives: Attentional bias toward drug-related cues is a characteristic of drug dependence and plays a detrimental role during drug withdrawal. The present study examined attentional bias in female individuals with drug dependence. We fo...

  • Article
  • Open Access
366 Views
12 Pages

21 October 2025

Background: Mental health issues among employees are a growing concern globally, particularly in high-stress environments such as Korean workplaces. This study was conducted to analyze the relationships between life stressors and depressive symptoms...

  • Article
  • Open Access
305 Views
16 Pages

P300 Spatiotemporal Prior-Based Transformer-CNN for Auxiliary Diagnosis of PTSD

  • Lize Tan,
  • Hao Fang,
  • Peng Ding,
  • Fan Wang,
  • Yuanyuan Wei and
  • Yunfa Fu

19 October 2025

Objectives: To address the challenges of subjectivity, misdiagnosis and underdiagnosis in post-traumatic stress disorder (PTSD), this study proposes an objective auxiliary diagnostic method based on P300 signals. Existing studies largely rely on conv...

  • Article
  • Open Access
472 Views
31 Pages

Dopaminergic Degeneration Differentially Modulates Primary Motor Cortex Activity and Motor Behavior in Hemiparkinsonian Rats

  • Suelen L. Boschen,
  • Julian Seethaler,
  • Shaohua Wang,
  • Wendy D. Lujan,
  • Jodi L. Silvernail,
  • Launia J. White,
  • Michael G. Heckman,
  • Rickey E. Carter,
  • Su-Youne Chang and
  • J. Luis Lujan

18 October 2025

Background/Goal: Parkinson’s disease (PD) disrupts dopaminergic transmission, leading to motor deficits and altered activity in the primary motor cortex (M1). While M1 modulation is critical for motor control, its response to dopaminergic degen...

  • Article
  • Open Access
474 Views
21 Pages

Aging, Cognitive Efficiency, and Lifelong Learning: Impacts on Simple and Complex Sentence Production During Storytelling

  • Silvia D’Ortenzio,
  • Francesco Petriglia,
  • Giulia Gasparotto,
  • Sara Andreetta,
  • Marika Gobbo and
  • Andrea Marini

18 October 2025

Objectives: This study investigated the effects of healthy aging on sentence production in narrative discourse and examined the role of cognitive abilities and Lifelong Learning (LLL) in mitigating age-related decline. Methods: Three hundred and seve...

  • Article
  • Open Access
340 Views
14 Pages

Disability and Non-Motor Symptoms in Multiple Sclerosis: Exploring Associations and Predictive Factors

  • Ana Jerković,
  • Ivona Stipica Safić,
  • Sanda Pavelin,
  • Nikolina Pleić,
  • Klaudia Duka Glavor,
  • Igor Vujović,
  • Joško Šoda,
  • Jasna Duranović and
  • Maja Rogić Vidaković

18 October 2025

Background/Objectives: The relationship between multiple sclerosis (MS) disability and co-occurring non-motor symptomatology is not well understood. This study examined the association between disability status and non-motor symptoms—sleep qual...

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Brain Sci. - ISSN 2076-3425Creative Common CC BY license