The Latest Exploration of Cerebrovascular Diseases: From Preclinical Research to Treatment
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurosurgery and Neuroanatomy".
Deadline for manuscript submissions: 3 February 2025 | Viewed by 460
Special Issue Editors
2. Department of Neuroradiology, Timone Hospital, Marseille, France
Interests: aneurysm wall biology; animal models for the study of endovascular technologies; cerebrovascular surgery and minimally invasive procedures; intraoperative technology; device development
Special Issues, Collections and Topics in MDPI journals
2. Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada
Interests: functional neuroimaging; brain hemodynamics; BOLD functional MRI to assess cerebrovascular reactivity in cerebrovascular diseases (brain AVM, large athero-sclerotic vessel occlusion, Moyamoya disease); role of surgical revascularization in acute stroke
Special Issue Information
Dear Colleagues,
The latest exploration of cerebrovascular diseases, which encompasses a range of conditions affecting blood flow to the brain and cerebral hemodynamic status, has marked significant advancements from preclinical research to clinical treatments. Preclinical studies have delved into the intricate mechanisms of these diseases, uncovering critical insights into risk factors, genetic predispositions, and molecular pathways. Breakthroughs in neuroimaging and biomarker identification have enhanced early detection and diagnosis, paving the way for more targeted interventions.
On the diagnostic and treatment front, innovative approaches are emerging. Novel, non-invasive, and quantitative imaging techniques to assess brain hemodynamics and collateral vessel status through innovative MRI methods shape our understanding and broaden the multimodal treatment options for various neurovascular diseases, including acute ischemic stroke. Cutting-edge therapies, such as neuroprotective drugs and advanced endovascular techniques, are showing promise in reducing the impact of strokes and other cerebrovascular events. Regenerative medicine, including stem cell therapy, offers hope for repairing brain damage and restoring function. Furthermore, personalized medicine is gaining traction, with treatments tailored to the individual’s genetic and clinical profile, improving outcomes and reducing adverse effects.
Integrating artificial intelligence and machine learning revolutionizes research and clinical practice, enabling more precise diagnosis, disease progression prediction, and treatment strategy optimization. This multi-faceted approach, from preclinical discoveries to personalized treatments, signifies a new era in the fight against cerebrovascular diseases, offering hope for improved patient outcomes and quality of life.
Dr. Basil Grüter
Dr. Martina Sebök
Guest Editors
Manuscript Submission Information
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Keywords
- intracranial aneurysm
- arterio-venous malformation (AVM)
- dural arterio-venous fistula (AVF)
- ischaemic stroke
- chronic steno-occlusive disease
