Sarcoma: Clinical Trials and Management

Dear Colleagues,

Sarcoma represents a heterogenous collection of mesenchymal neoplasms originating in the soft tissue and bone. There are over 50 different histologic subtypes of sarcoma, and these differ by differentiation, clinical behavior, genetics, age of occurrence, and response to different therapies.  The optimal treatment of sarcoma can vary significantly between different histologic subtypes. 

Over the past decade, several innovative therapies have revolutionized the field of oncology and have challenged conventional notions of cancer treatment. New molecular targets have been identified, and immunotherapy has dramatically changed the treatment landscape for multiple malignancies, including several sarcoma subtypes. 

In this present Special Issue, we are particularly interested in manuscripts reporting original findings or updated literature reviews concerning the treatment of sarcoma. We seek to highlight innovative strategies that may lead to improvements in the management of bone and soft tissue sarcomas.

Prof. Dr. Mohammed M. Milhem
Dr. John Rieth
Guest Editors

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