Human Papillomavirus (HPV)-Associated Cancers
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Infectious Agents and Cancer".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 26
Special Issue Editor
Special Issue Information
Dear Colleagues,
In ancient Roman and Greek texts, lesions that are similar to present-day genital warts were described, providing the earliest evidence of infections by the human papillomavirus (HPV). At the start of the 20th century, pioneering experiments demonstrated the contagious nature of warts and their viral origins. Anecdotal reports describing the spontaneous conversion of genital warts into squamous cell carcinomas ushered in an era of clinical research that aimed to establish an association between HPV infection and cancer. Ground-breaking research in the 1980s definitively identified two HPV genotypes, HPV type 16 (HPV16) and HPV type 18 (HPV18), as the causative agents of cervical cancer. Today, it is well established that infection with certain HPV types can give rise to not only cervical cancers, but also vaginal, vulvar, anal, penile, and head and neck cancers.
After a century from those initial experiments, HPVs are some of the most studied viruses in the world due to their sexual mode of transmission and their collective role in causing an estimated 4.1% of the global burden of cancer. Importantly, despite the availability of effective vaccines, some HPV-associated cancers are amongst the fastest rising cancers in certain geographical regions.
This Special Issue will focus on cancers associated with HPV infections, and we welcome authors to submit original research or comprehensive reviews that highlight the current research landscape on HPV-associated cancers that will advance our current understanding of this potent biological carcinogen.
Dr. Steven F. Gameiro
Guest Editor
Manuscript Submission Information
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Keywords
- anal cancer
- cervical cancer
- head and neck cancers
- oropharyngeal cancer
- penile cancer
- vaginal cancer
- vulvar cancer
- HPV
- human papillomavirus
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