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Cancers
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The Application of Laparo-Endoscopic and Robotic Surgery in Cancer Treatments...
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The Application of Laparo-Endoscopic and Robotic Surgery in Cancer Treatments and Research

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 2068

Special Issue Editor

Dr. Yutaro Kato

E-Mail Website
Guest Editor
Department of Advanced Robotic and Endoscopic Surgery, Fujita Health University, Toyoake Aichi 470-1192, Japan
Interests: hepatobiliary and pancreatic surgery; gastrointestinal cancer surgery; minimally invasive surgery; laparoscopic liver resection; robotic liver resection; laparoscopic pancreatic resection; endoscopic surgery; liver cancer; biliary cancer; pancreatic cancer

Special Issue Information

Dear Colleagues,

Due to the introduction of and global spread of minimally invasive surgical approaches and platforms, surgical treatments in the management of cancer have rapidly advanced over the last three decades. Laparo-endoscopic approaches and newly developed robotic platforms in cancer surgery have reportedly conferred patient-friendly, minimal invasiveness, superior perioperative outcomes and acceptable oncologic outcomes in selected patients compared to those of conventional open surgery. On the other hand, along with technical refinements and innovations, the expansion of surgical indication is still underway in minimally invasive surgery for ill-conditioned cancers and patients.

This Special Issue will highlight the present status, recent advances, innovative techniques, clinicopathological and molecular research, and future innovation and research seeds in minimally invasive surgical approaches to cancer treatments in a variety of organs.

Dr. Yutaro Kato
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cancer
  • minimally invasive surgery
  • laparoscopic surgery
  • endoscopic surgery
  • robotic surgery
  • telesurgery
  • periop-erative outcomes
  • oncologic outcomes
  • clinicopathology
  • molecular biology

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Published Papers (2 papers)

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Research

14 pages, 991 KiB  
Article
Upfront Surgery vs. Endoscopic Stenting Bridge to Minimally Invasive Surgery for Treatment of Obstructive Left Colon Cancer: Analysis of Surgical and Oncological Outcomes
by Mauro Marzano, Paolo Prosperi, Gian Luca Grazi, Fabio Cianchi, Luca Talamucci, Damiano Bisogni, Lapo Bencini, Manuela Mastronardi, Tommaso Guagni, Agostino Falcone, Jacopo Martellucci, Carlo Bergamini and Alessio Giordano
Cancers 2024, 16(23), 3895; https://doi.org/10.3390/cancers16233895 - 21 Nov 2024
Viewed by 778
Abstract
Background: Left colon cancer obstruction treatment is a debated topic in the literature. Stent placement is effective as a bridge-to-surgery strategy, but there are some concerns about the oncological safety for the reported higher risk of local and peritoneal recurrence. This study aims [...] Read more.
Background: Left colon cancer obstruction treatment is a debated topic in the literature. Stent placement is effective as a bridge-to-surgery strategy, but there are some concerns about the oncological safety for the reported higher risk of local and peritoneal recurrence. This study aims to compare the surgical and oncological outcomes of patients treated with stent followed by elective surgery with those treated with primary resection. Methods: This is a retrospective observational study. We included patients of both sexes, ≥18 years old, with a histological diagnosis of intestinal adenocarcinoma, and admitted to our hospital for left colon cancer obstruction demonstrated by CT scan without metastasis or perforation. They were treated through primary resection (PR) or stent placement followed by elective surgery (SR). The two groups were compared for general characteristics, surgical outcomes, and oncological outcomes (metastasis and local recurrence) at 30 days, 90 days, 1 year, and 3 years. Post-operative quality of life (QoL) was also investigated. Results: The SR group showed a shorter hospital stay, a lower post-operative mortality, a lower stoma rate at 1 year, and a higher number of minimally invasive procedures. Oncological outcomes were not different compared to the PR group. The SR group demonstrated better QoL in two out of six items on the EQ-5D-5L test. Conclusions: Stent placement as a bridge-to-surgery strategy is feasible and provides better surgical outcomes in terms of post-operative complications, surgical approach, stoma rate, and QoL. Oncological outcomes were not reported differently, but further studies should be conducted to better evaluate this aspect. Full article
(This article belongs to the Special Issue The Application of Laparo-Endoscopic and Robotic Surgery in Cancer Treatments and Research)
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11 pages, 814 KiB  
Article
Robotic Major Hepatectomy in Elderly Patient
by Antonella Delvecchio, Maria Conticchio, Riccardo Inchingolo, Francesca Ratti, Paolo Magistri, Andrea Belli, Graziano Ceccarelli, Francesco Izzo, Marcello Giuseppe Spampinato, Nicola De’ Angelis, Patrick Pessaux, Tullio Piardi, Fabrizio Di Benedetto, Luca Aldrighetti and Riccardo Memeo
Cancers 2024, 16(11), 2083; https://doi.org/10.3390/cancers16112083 - 30 May 2024
Cited by 1 | Viewed by 694
Abstract
Background: the role of minimally invasive liver surgery has been progressively developed, with the practice increasing in safety and feasibility also with respect to major liver resections. The aim of this study was to analyze the feasibility and safety of major liver resection [...] Read more.
Background: the role of minimally invasive liver surgery has been progressively developed, with the practice increasing in safety and feasibility also with respect to major liver resections. The aim of this study was to analyze the feasibility and safety of major liver resection in elderly patients. Methods: data from a multicentric retrospective database including 1070 consecutive robotic liver resections in nine European hospital centers were analyzed. Among these, 131 were major liver resections. Patients were also divided in two groups (<65 years old and ≥65 years old) and perioperative data were compared between the two groups. Results: a total of 131 patients were included in the study. Operative time was 332 ± 125 min. Postoperative overall complications occurred in 27.1% of patients. Severe complications (Clavien Dindo ≥ 3) were 9.9%. Hospital stay was 6.6 ± 5.3 days. Patients were divided into two groups based on their age: 75 patients < 65 years old and 56 patients ≥ 65 years old. Prolonged pain, lung infection, intensive care stay, and 90-day readmission were worse in the elderly group. The two groups were matched for ASA and Charlson comorbidity score and, after statistical adjustment, postoperative data were similar between two groups. Conclusions: robotic major liver resection in elderly patients was associated with satisfying short-term outcomes. Full article
(This article belongs to the Special Issue The Application of Laparo-Endoscopic and Robotic Surgery in Cancer Treatments and Research)
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