State-of-the-Art and Perspectives in the Treatment of Hormone-Receptor-Positive Breast Cancer

Dear Colleagues,

Hormone-receptor-positive and HER2-negative breast cancer is the most common type of breast cancer. Endocrine therapy is the mainstay of treatment, and many patients do not need any other treatment. In both advanced and early cancer, additional therapies aiming at overcoming resistance have been developed. The emergence of novel targeted therapy in combination with endocrine therapy has shown improvement in outcomes, and may even make cytotoxic chemotherapy unnecessary in more patients in the future. In particular, CDK4/6 inhibitors and novel SERDs are promising options for the future. In this Special Issue of Cancers, we welcome original research and comprehensive review articles focusing on recent developments in the treatment of hormone-receptor-positive breast cancer, including special topics such as premenopausal patients and neoadjuvant treatment approaches.

Prof. Dr. Michael Gnant
Guest Editor

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