Cancer Cells Fostered Microenvironment in Metastasis
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Metastasis".
Deadline for manuscript submissions: 30 July 2025 | Viewed by 4220
Special Issue Editor
Special Issue Information
Dear Colleagues,
The tumour microenvironment (TME) has been extensively investigated in recent decades for the involvement of other types of cells and immune responses during the development and progression of various solid malignant tumours. Meanwhile, the implication of TME in drug resistance and new therapeutic approaches also attracts attention and research interest from both scientists and clinicians. The important and dominant role played by cancer cells in the TME suggests their capability to foster a supportive niche for an invasive growth/expansion and also communicate with a distant tissue/organ for a subsequent spread and colonization. The present Special Issue aims to focus on the cancer cells the express and release particles/molecules in the multiple-step process of distant metastases to provide a favourable TME at both primary and secondary sites. Review, research articles and short editorials are welcomed that work to collectively tackle those challenges encountered by patients, clinicians and scientists by highlighting the cancer cells that foster a tumour microenvironment during the process of distant dissemination.
Dr. Lin Ye
Guest Editor
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Keywords
- cancer cells
- tumour microenvironment
- metastasis
- fibroblast
- immune cells
- extracellular ma-trix
- adhesion
- migration
- invasion
- drug resistance
- target therapy
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