Clinical Applications of Precision Diagnosis for Thyroid Cancers and Its Clinical Use for Treatments Choice

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Clinical Research of Cancer".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 1

Special Issue Editors


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Guest Editor
Department of Clinical and Experimental Medicine, University Hospital, 98125 Messina, Italy
Interests: thyroid cancer; cytokines; molecular biology; autoimmunity; nanoparticles
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Guest Editor
Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
Interests: chemokines; autoimmune thyroid disorders; thyroid cancer; primary cell cultures; autoimmunity
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Guest Editor
Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University Hospital "G. Martino" of Messina, Via Consolare Valeria 1, 98125 Messina, Italy
Interests: general surgery; breast and endocrine surgery; minimally invasive surgery; traumatology and innovative; thyroid cancer; breast cancer; autoimmunity; endocrine surgery surgical techniques development
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Special Issue Information

Dear Colleagues,

Nearly 5% of thyroid nodules in adult patients are malignant. Thyroid cancer (TC) includes well-differentiated types, which show a good prognosis, and undifferentiated varieties with a poor prognosis. TCs can originate from follicular or parafollicular C cells.

Precision diagnosis (PD) addresses TC management considering that a correct diagnosis should be useful in choosing an appropriate treatment and therefore in increasing the chances of a favorable outcome. The objectives of PD are not only limited to the development of targeted therapies but also to the role played in the prevention and prediction of TC by assessing their risk of developing tumors. In addition, PD can monitor TC for epidemiological reporting and benefit from the artificial intelligence support.

Therefore, PD for TC represents collective research involving endocrinologists, surgeons, pathologists, oncologists, geneticists, epidemiologists, and computer scientists. Nevertheless, the technologies needed to assess PD are not equally accessible to all countries, highlighting a problem of health inequalities.

This Special Issue focuses on the contributions from different medical disciplines to achieve PC in TC cases, and on the effective applications of PD in common clinical practices of TC, without neglecting the issue of health inequalities.

Dr. Maria Trovato
Dr. Silvia Martina Ferrari
Prof. Dr. Fausto Famà
Guest Editors

Manuscript Submission Information

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Keywords

  • thyroid cancer
  • precision diagnosis
  • clinical management
  • molecular tests
  • molecular therapeutic targets
  • thyroid cancer epidemiology
  • artificial intelligence
  • health inequalities

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