Possible Biomarkers in Oral Tumors and Their Clinical Significance
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Biomarkers".
Deadline for manuscript submissions: 30 November 2024 | Viewed by 3084
Special Issue Editor
Interests: oral cancer; head and neck tumors; oral and maxillofacial surgery; invasion and metastasis; prognostic markers
Special Issue Information
Dear Colleagues,
Oral cavity is the site of origin for a wide variety of tumors. Oral tumors are generally easy to access by visual inspection and palpation, and most definitive diagnoses are determined by the histopathological examination after biopsies. However, the diagnosis may often be difficult due to their histopathological varieties, especially in tumors originated from tooth germ, minor salivary gland, and mesenchyme, and so on.
On the other hand, squamous cell carcinoma (SCC) is a typical malignancy in the oral cavity, the definitive diagnosis is comparatively easy because of their accessibility and characteristic histology. Although oral SCC is generally treated with surgery, radiotherapy, chemotherapy, immunotherapy, or their combination, the prognosis and the prediction of therapeutic effect are mainly determined by the histopathological degree of invasion and differentiation. Concerning the biomarker for oral SCC, serum SCC antigen is clinically applied but is not reliable as a sensitive biomarker.
In this special issue, researchers who are a head and neck oncologist and has a wealth of basic data will discuss biomarkers that are expected to be applied clinically in relation to the diagnosis, recurrence, metastasis, or prognosis of oral tumors.
Prof. Dr. Daisuke Uchida
Guest Editor
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Keywords
- oral squamous cell carcinoma
- oral tumor
- biomarkers
- diagnosis
- prognosis
- treatment
- prediction