Cytologic Features of Tumor
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (30 November 2019) | Viewed by 46715
Special Issue Editors
Interests: fine-needle aspiration cytology; immunocytochemistry; cell biology; epithelial-to-mesenchymal transition; mesothelial cells; carcinoma-associated fibroblasts; thyroid cytopathology; brain tumors
Special Issues, Collections and Topics in MDPI journals
Interests: fine-needle aspiration cytology; cervical cytology; cervical screening; immunocytochemistry; salivary gland neoplasms; thyroid cytopathology; reactive lymphadenopathies
Interests: fine-needle aspiration cytology; molecular pathology; urinary cytology; renal neoplasms; testicular pathology; immunohistochemistry
Special Issue Information
Dear Colleagues,
Fine-needle aspiration cytology (FNAC) is a relatively young discipline within diagnostic pathology. It has pros and cons when compared to the gold standard pathologic diagnosis of histopathology. Its main advantage is that FNAC is a minimally invasive procedure that permits easy, safe, and rapid sampling of tumors as well as access to locations where a tissue biopsy is very difficult or impossible to perform. Its principal limitation is that sometimes the amount of material obtained is not enough for all the necessary studies. Its reduced invasiveness has permitted the appearance in the diagnostic scenario of endoscopic, ultrasound-guided FNAC of mediastinal, pancreatic, and other abdominal lesions. Furthermore, it has greatly contributed to the diagnosis and specific treatment of pulmonary and pancreatic neoplasms. Other aspects of diagnostic cytology such as effusion cytology, cervical cytology, and intraoperative cytology have also played an important role in offering a minimally invasive pathologic diagnosis.
The latest advances in molecular biology, more precisely next-generation sequencing, are certainly going to revolutionize the diagnosis of neoplasms. We all have great expectations in these methods as well as in liquid biopsy. To what extent is diagnostic pathology, as we know it today, going to be necessary? In this new diagnostic context, cytology establishes an ideal link between diagnostic morphology and molecular studies. Because of their low invasiveness, FNAC samples are ideal for obtaining material for molecular studies of solid tumors. This Special Issue will highlight recent advances in basic aspects of clinical cytopathology as well as the bridging role between diagnostic morphology and molecular studies offered by FNAC. Original research articles, short clinical series, as well as reviews on all aspects of diagnostic cytopathology are welcome.
Prof. Dr. José A. Jiménez Heffernan
Dr. Blanca Vicandi
Prof. Dr. Pilar González-Peramato
Guest Editors
Manuscript Submission Information
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Keywords
- cytopathology
- fine-needle aspiration cytology
- diagnostic cytology
- endoscopic ultrasound-guided FNA
- intraoperative cytology
- immunocytochemistry
- molecular cytopathology
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