Female Malignancies and Immunotherapy: What’s New? (Volume II)
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Immunology and Immunotherapy".
Deadline for manuscript submissions: closed (5 July 2024) | Viewed by 4339
Special Issue Editors
Interests: human immunology; innate immunity; human natural killer cells; tumor immunology; immunotherapy; immune checkpoints
Special Issues, Collections and Topics in MDPI journals
2. Department of Surgical Sciences and Integrated Diagnostic (DISC), School of Medicine, University of Genoa, 16132 Genoa, Italy
Interests: breast cancer; breast cancer surgery; breast reconstruction; breast cancer molecular subtypes; neo/adjuvant therapy for breast cancer
2. Anatomic Pathology University Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy
Interests: gynecologic pathology; placental & fetal pathology; molecular pathology
Special Issues, Collections and Topics in MDPI journals
Interests: human natural killer cells; NK cell receptors; activating NK receptors; NKG2A; KIRs; PD-1; cancer immunosurveillance; cancer biology; tumor microenvironment; microRNAs; immunotherapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is a continuation of our previous Issue, “Female Malignancies and Immunotherapy: What’s New?”
(https://www.mdpi.com/journal/cancers/special_issues/Malignancies_Immunotherapy)
Current emerging therapies for solid tumors include various immunotherapeutic approaches, such as immune-checkpoint inhibitors (ICIs), which have gained considerable attention because of their impressive treatment outcomes in different tumor types. Unfortunately, benefits have been seen only in a small percentage of patients with solid tumors. For this reason, it is necessary to improve our knowledge on immune checkpoints (ICs) and on the tumor microenvironment.
In the cancer treatment context, T cells have always been considered primarily responsible for the beneficial effect of immunotherapy. However, NK cells are also now seen as a promising cancer immunotherapy tool due to their ability to kill malignant cells without toxicity towards healthy cells. However, cancers develop escape strategies to alter immune cells’ anti-tumor activity.
Among existing cancers, female malignancies present challenges in terms of diagnosis and the efficacy of clinical approaches. Indeed, female tumors are often characterized by an immunosuppressive tumor environment, able to resist not only immune system attack, but also advanced immunotherapeutic approaches.
The goal of this Special Issue, “Female Malignancies and Immunotherapy: What’s New? 2.0”, is to contribute to dissecting the molecular and cellular immunological mechanisms involved in female malignancies’ progression and metastasis. This information will provide new insights that are crucial for the development of new immunotherapeutic strategies and for the improvement of combination strategies in the patient-specific treatment of female cancers.
Dr. Silvia Pesce
Dr. Piero Fregatti
Dr. Valerio Gaetano Vellone
Dr. Emanuela Marcenaro
Guest Editors
Manuscript Submission Information
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Keywords
- breast cancer
- ovarian cancer
- cervical cancer
- natural killer cells
- immunotherapy
- cancer immunology
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