Application of Ultrasound in Breast Cancer
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 5831
Special Issue Editor
Special Issue Information
Dear Colleagues,
As ultrasound rapidly continues to develop far beyond anatomical imaging to a state-of-the-art functional and molecular imaging modality, new opportunities for both diagnosis and the monitoring of responses to therapy in breast cancer are opening up. The exciting new paradigm of ultrasound microvascular imaging, which encompasses techniques such as super-resolution imaging, acoustic angiography and micro-Doppler imaging, means we can now probe the tumour microenvironment using ultrasound. Recent innovations in ultrasound-contrast nanoagents, which can be targeted to tumour cell receptors, broaden the scope for the development of highly sensitive diagnostic tools and for the characterization and spatial mapping of tumour biology on a molecular level. Elastography and ultrasonic tissue characterisation hold the ability to interrogate the evolving structure of progressive or regressive cancer. In addition to improving the detection and management of breast cancer clinically, all of these techniques can be used preclinically to support the development of cancer therapies. Importantly, ultrasound can also be used as a cancer therapeutic itself; a combination of microbubble contrast agents with low-intensity ultrasound is a promising new technology to both aid drug delivery and increase tumour radiosensitivity. Ablative ultrasound therapies and hyperthermia can also be used to complement drug and radiation treatments.
This Special Issue aims to capture a cross section of the exciting new possibilities ultrasound offers for better detection, diagnosis, assessment of treatment response, and treatment of breast cancer. We are interested in the development and validation of novel ultrasound technologies applied to breast cancer, as well as the use of ultrasound to elucidate new understandings of breast cancer biology, the tumour microenvironment, and the mechanisms underlying response or resistance to cancer therapies.
Dr. Emma J. Harris
Guest Editor
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Keywords
- ultrasound
- functional imaging
- elastography
- molecular imaging
- breast cancer
- ultrasound therapy
- nanoparticles
- drug delivery
- vascular imaging
- tumour microenvironment
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