Cancer Stem Cells in the Tumor Microenvironment—Models and Mechanisms of Interaction in Epithelial Cancers
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: closed (20 July 2023) | Viewed by 408
Special Issue Editors
Interests: miRNAs; cancer; personalized medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Solid cancer is a collection of different cell types embedded in extracellular matrices in constant interaction with the rest of the human body. Tumor growth, in this context, requires a dynamic interplay of cancer stem cells with other cell types, e.g., stroma and immune cells and exchange of multiple factors, like nutrients and signaling molecules. The interactome on a cellular level is considered to be key to unsolved issues like resistance, progression, invasion and metastasis. Therefore, in this Special Issue, we wish to collect the latest insights on this dynamic interplay from cancer stem with the tumor microenvironment in the form of original research and review articles. We encourage submissions on the topic of direct cell–cell interaction, 3D modeling of cellular cross-talk as well as identification of factors and signaling pathways in the tumor microenvironment influencing proliferation, migration, invasion and self-renewal of cancer stem cells. The manuscripts should focus on epithelial tumors and their biology. We look forward to receiving your contributions.
Dr. Jochen Maurer
Dr. Bogdan-Tiberius Preca
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer stem cells
- tumor microenvironment
- cell–cell interaction
- extracellular matrices
- tumor progression
- EMT
- cell fate decisions
- self-renewal
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