Innate Immunosurveillance of Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Immunology and Immunotherapy".
Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 4054
Special Issue Editor
Interests: immune evasive mechanisms; tumor–stroma interactions; metastasis; engineering immune cells; TGF-b biology
Special Issue Information
Dear Colleagues,
Innate immune cells, including macrophages, neutrophils, dendritic cells (DCs), and innate lymphoid cells (ILCs), are the first line of defense against cancer development and infections. These cells respond to initial perturbations in the tissue, which can result in either control or even prevention of tumor initiation and progression. But, as tumors develop immune evasive mechanisms, innate immune cells can also facilitate tumor progression and metastasis. The overall outcome of the innate immunosurveillance is determined in the specific context of the tumor microenvironment and differs by the tumor type. Therefore, understanding the influence and mechanisms underlying both pro- and anti-tumor effects of the innate immune system is crucial in fighting cancer.
This Special Issue will collect a series of reviews and original articles describing basic science, preclinical, and clinical investigations, covering all aspects of innate immune surveillance from tumor initiation, progression, and metastasis. Potential topics include but are not limited to tumor immune microenvironments with emphasis on innate immune cells, innate immune receptors and signaling, molecular mechanisms of innate immune evasion, engineering innate immune cells, novel immunotherapies, and mechanisms of resistance to immunotherapies.
Dr. Venkateshwar G. Keshamouni
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- tumor microenvironment
- innate immune cells
- inflammation
- DAMP and PAMP signaling
- metastasis
- immune evasion
- engineering immune cells
- immunotherapy
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