The Link between Obesity and Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Epidemiology and Prevention".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 2190
Special Issue Editor
Special Issue Information
Dear Colleagues,
We are pleased to invite you to submit articles focused on molecular, pharmacologic, hormonal, immunologic, microbiologic, genetic and epigenetic mechanisms, and modulators alone and/or in combination with lifestyle or metabolic-bariatric surgical interventions to disrupt the obesity cancer linkage. In this Special Issue, original research articles and reviews are welcome.
Overweight and obesity constitute a major worldwide pandemic affecting over 2 billion individuals. They are causally related to significant comorbidities, including the promotion, acceleration, and worsening of the prognosis of multiple malignancies. Obesity is estimated to be associated with 20% cancer deaths in women and 14% in men. Many consequences of obesity have been shown to promote the obesity cancer linkage, including inflammatory, metabolic, and hormonal processes, mediated by adipokines, cytokines, hormones, microbiome dysbiosis, and epigenetic changes. Intentional weight loss strategies, including intensive lifestyle alterations and/or metabolic-bariatric surgery, clearly ameliorate some of the metabolic effects of obesity, but only show modest benefits in terms of decreasing cancer incidence and/or reducing cancer-related mortality.
This Special Issue of Cancers aims to more precisely define obesity cancer linkages; more specifically identify the mechanisms by which obesity-associated cancer-promoting processes actually mediate their effects; and to focus on identifying strategies, agents, and interventions which alone and/or in combination will disrupt the obesity cancer linkage.
I look forward to receiving your contributions.
Prof. Dr. Nathan Berger
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- obesity associated cancers
- obesity cancer linkage
- linkage disruption
- adipokines
- cytokines
- epigenetics
- microbial dysbiosis
- hormonal changes
