New Horizons in Particle Therapy
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 27713
Special Issue Editors
Department of Radiation Oncology, University Hospital Heidelberg, Heidelberg, Germany
National Center of Oncological Hadrontherapy, Pavia, Italy
Interests: Monte Carlo; fast computing; treatment planning; biophysical modelling; novel particle therapy modalities
German Cancer Consortium (DKTK), Heidelberg, Germany
Heidelberg Institute of Radiation Oncology (HIRO), German Cancer Research Center (DKFZ), Heidelberg, Germany
Heidelberg Ion-Beam Therapy Center (HIT), Heidelberg, Germany
Interests: particle radiobiology and radiotherapy; irradiation induced DNA damage response and tumor–stroma interactions
Interests: pediatric oncology; pediatric brain tumors; neuro-oncology; proton beam therapy; ion beam therapy; high-precision radiotherapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues
Charged particle therapy (CPT) is an emerging field in cancer therapy, and with recent technological advances, cutting-edge modalities are more accessible to the general public than ever. As opposed to conventional photon-based radiotherapy, light and heavy ion beams promise more favorable therapeutic properties for cancer therapy, affording clinicians the power to deliver radiation doses to tumors with high precision and conformity while significantly sparing surrounding healthy tissues and critical anatomic structures. Through application of state-of-the-art delivery systems, such as intensity modulated particle therapy, radio-resistant diseases with poor prognosis using standard care can be effectively treated.
To fully exploit CPT with the utmost precision, modeling and predicting biophysical processes elicited from particle beam interactions within the human body must be performed on both macroscopic and microscopic scales. Moreover, with numerous proton facilities sprouting worldwide, recent reports emphasize the urgency of improving current clinical practices in handling biological effect uncertainty. To this end, we believe developing and integrating advanced computational methods and biological perspectives for CPT into clinical environments is vital.
In this Special Issue, we welcome submissions from the following categories:
- Novel particle therapy modalities such as helium, oxygen ion beams, combined ion treatments, FLASH, etc.;
- Advanced computation and optimization techniques in particle therapy (e.g. analytical, Monte Carlo, machine learning);
- Breakthroughs in patient-specific particle therapy treatments;
- Novel insights in biological response of tumors and normal tissues to particle therapy;
- Expansion and evolution of fundamental biophysical knowledge of radiation induced effects using particle beams through biological experimental study and/or implementing sophisticated models to describe biological phenomena;
- Assessment and interpretation of clinical data to link physical, biological, and clinical endpoints to treatment outcome in CPT.
Dr. Andrea Mairani
Dr. Dokic Ivana
Dr. Semi B. Harrabi
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- particle therapy
- treatment planning
- Monte Carlo
- fast computing
- biophysical models
- quality assurance
- patients’ outcome
- normal tissue reaction
- radiobiology