Catalyzed Synthesis of Chiral Amines

Dear Colleagues,

Chiral amines are valuable constituents of many important pharmaceutical compounds or their intermediates. It is estimated that nearly 50% of pharmaceutical drugs contain chiral amine scaffolds in their structures. The requisite amines are scarce in nature, and their industrial production mainly relies on the metal-catalysed, traditional organic synthesis. On the other hand, tremendous advancements in biocatalytic methods for chiral amines have been achieved during the last decades. Enzyme catalysis provides green and selective tools for the enantioselective synthesis of chiral amines.

This Special Issue aims to cover recent updates and novel trends in the synthesis of chiral amines. We invite the scientific community to submit their contributions in the form of original research papers and review articles that provide new insights and emphasize aspects of fundamental and applied research areas.

Contributions should be related, but not limited, to the following:

• Green synthesis of chiral amines
• Discovery of novel bicayalysts and/or engineering of known biocatalysts
• Development and application of novel immobilized biocatalysts
• Design and construction of new whole-cell biocatalysts
• Novel catalytic reactions for the synthesis of chiral amines.

Prof. Hyungdon Yun
Dr. Mahesh D. Patil
Guest Editors

Manuscript Submission Information

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