The Role of Immune Cells in Ocular Diseases
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Immunology".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 2048
Special Issue Editor
Interests: inflammation; ocular inflammatory diseases; immune privilege; innate immunity; adaptive immunity; tissue homeostasis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The eye and immune systems use strategies to maintain the ocular immune privilege by regulating the innate and adaptive immune responses, which include immunological ignorance, peripheral tolerance to eye-derived antigens, and the intraocular immunosuppressive microenvironment. Resident immune cells play an important role in local immunological homeostasis, and their responses can be protective or reparative. Local and systemic inflammatory and immune-mediated disorders affecting the eye are propagated not only by newly infiltrating inflammatory cells, but also by the accompaniment of immune cells normally present in non-inflamed ocular tissues.
Due to the different structures and tissue types in the eye, the immune responses to pathological or traumatic injury are distinct in different regions of the eye and excessive immune activity and cytokine release by immune cells can compromise visual acuity by inducing inflammation and fibrosis.
The aim of this Special Issue is to collect original research findings and reviews discussing the ocular immune system (including distribution, phenotype and function) in healthy eyes and in immune-related ocular diseases. We also welcome manuscripts discussing potential strategies for modulating immune responses in translational approaches.
Dr. Malihe Eskandarpour
Guest Editor
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