Relationship between Inflammation and Aryl Hydrocarbon Receptor Pathway - Second Edition
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Signaling".
Deadline for manuscript submissions: closed (15 March 2023) | Viewed by 5790
Special Issue Editor
Interests: inflammation; aryl hydrocarbon receptor; cell physiology; cell signaling; endocrine interference; nonsteroidal anti-inflammatory drugs (NSAIDs)
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Aryl hydrocarbon Receptor (AhR) has long been known as an endogenous biosensor linking different environmental stresses to cellular homeostatic mechanisms and detoxification processes. Its evolutionary conservation and the gene sets that are responsive to this transcription factor highlight its participation in basic physiological processes such as cell growth and differentiation, and in the inflammatory response. In fact, AhR plays a central modulatory role in the immune system and is also emerging as a key player in inflammatory processes, which are triggered by several physiologic and pathologic settings in different tissues. In the last two decades, research with AhR knockout mice highlighted AhR participation in the homeostasis of almost all physiologic systems with both genomic and non-genomic mechanisms that frequently interact with inflammation pathways. In addition, the variety of endogenous and exogenous ligands that interfere with AhR signalling points out its role beyond detoxification processes and is helping in understanding its contribution in cell transition to the inflammatory state and in its resolution.
This call meets the growing need to draw a coherent framework describing the participation of AhR pathway in the management of inflammatory processes in different cell types. We will appreciate papers reporting the contribution of AhR, both in the onset and in the resolution of inflammation in physiological and pathological settings, including the recent SARS-CoV-2-induced inflammation. Evolutionary perspectives about AhR functions are also welcome.
Prof. Dr. Tiziana Guarnieri
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- aryl hydrocarbon receptor
- biosensor
- xenobiotics
- ligands
- inflammation
- immune system
- homeostasis
- cellular signalling
- evolution
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
