Cell-Penetrating Peptides (CPPs) in Cancer: From Molecular Mechanisms to Applications in Diagnostic and Therapeutic Opportunities
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: closed (30 April 2024) | Viewed by 10979
Special Issue Editors
Interests: brain tumors; molecular biology; protein/peptide chemistry; cell biology; basic and translational cancer biology
Special Issues, Collections and Topics in MDPI journals
Interests: the interface of materials, biomedicine and energy, with applications in drug and gene delivery, protein-lipid interactions, emulsification, coating, energy storage and conversion
Interests: peptide design and biointerfaces; peptides for drug delivery; microfluidic device development; nano-functional materials; food science and biomedicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cell-penetrating peptides (CPPs), also known as protein transduction domains (PTDs), are generally short peptides that have been widely studied. Since the first CPP was discovered ~30 years ago, several novel mechanisms and applications of CPPs have been reported.
Given that synthetic and natural CPPs can deliver several types of bioactive cargo, including proteins, peptides, DNA/RNA and chemotherapeutic and imaging agents, into cells, CPPs have been used in preclinical and clinical research. It is evident that CPPs have gained significant attention over the last decade, and they have great potential to develop the next-generation approaches to fight against cancer.
As such, we welcome original research articles, reviews, and perspectives focusing on recent advances in cancer research with CPPs. Manuscripts describing solely bioinformatics or in silico computational analysis that are not accompanied by biological validation are out-of-scope for this topic. We are looking for contributions that primarily focus on CPPs for various types of cancer, including rare diseases.
Dr. Tohru Yamada
Prof. Dr. Pu Chen
Dr. Lei Zhang
Guest Editor
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Keywords
- tumors
- cellular internalization
- targeting delivery
- cargo molecule conjugations
- tumor imaging
- toxicity