New Trends and Advances in Diagnosis and Prognosis of Head and Neck Cancer from Carcinogenesis to Future Molecular Targeted Therapies
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 23453
Special Issue Editors
Interests: stem cell biology; regenerative medicine; immunopathology; molecular biology; cancer stem cells biology
Special Issues, Collections and Topics in MDPI journals
Interests: epithelial-mesenchymal transition; colorectal carcinoma; precancerosis and carcinoma of the head and neck; inflammatory bowel disease; organ fibrosis
Special Issues, Collections and Topics in MDPI journals
Interests: head and neck cancer; maxillofacial surgery; prognostic biomarkers; cancer biology; immunohistochemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Head and neck cancer is a heterogenous malignancy with high mortality and increasing incidence worldwide. Late diagnosis, rapid tumor growth, poor response to radiochemotherapy and early local recurrence are still key challenges in modern treatment. Growing evidence suggests that the highly aggressive behaviour of head and neck cancer may be an effect of cancer stem cells and abnormalities in the signaling pathways associated with them. Despite recent advances in therapeutic strategies, the 5-year survival rate has remained the same in the last decades at about 50%. For this reason, further studies elucidating head and neck cancer biology are urgently required to improve the survival of patients.
We are delighted to present this Special Issue of Cells that is focused on the latest advances and future trends in the diagnosis, prognosis and treatment of head and neck cancer. This Special Issue will present original research articles as well as up-to-date review papers that show cellular and molecular mechanisms of head and neck cancer and, in particular, new specific biomarkers or potential therapy targets that may allow us to better stratify the prognosis of patients and improve their clinical outcome. We would like to encourage head and neck cancer researchers around the world to submit their manuscripts to this Special Issue.
Prof. Dr. Julia Bar
Dr. Nina Zidar
Dr. Piotr Cierpikowski
Guest Editors
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Keywords
- head and neck cancer
- oral cancer
- biomarker
- prognosis
- carcinogenesis
- oral premalignant lesions
- cancer stem cells
- signaling pathways
- molecular targeted therapy
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