Metabolic Hallmarks in Cancer
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Metabolism".
Deadline for manuscript submissions: 20 May 2025 | Viewed by 93
Special Issue Editors
Interests: cancer stem cells; cancer metabolism; tumour recurrence and metastasis; drug resistance; clinical trials
Special Issues, Collections and Topics in MDPI journals
Interests: metabolic interactions in the tumor microenvironment; mechanisms through which oxidative stress induces cancer cells to proliferate and resistance to cell death; the role of autophagy in cancer cell aggressiveness
Interests: cancer stem cells; cancer metabolism; tumor recurrence and metastasis; drug resistance; drug discovery
Special Issue Information
Dear Colleagues,
Cancer is a complex disease that disrupts the delicate balance of cellular processes, with metabolic reprogramming being a central hallmark. This reprogramming is a result of the intricate interplay between cellular and molecular mechanisms that enable cancer cells to adapt, survive, and proliferate in a nutrient-limited and hypoxic tumor microenvironment. The cellular and molecular aspects of cancer metabolism involve a shift in energy production pathways, alterations in biosynthetic processes, and the exploitation of metabolic intermediates for the synthesis of macromolecules essential for tumor growth.
This Special Issue will explore the fundamental metabolic adaptations that cancer cells undergo, such as the Warburg effect, the reverse Warburg effect, glutamine addiction, and the pentose phosphate pathway's role in nucleotide synthesis. By focusing on these cellular and molecular aspects, we aim to provide insights into the metabolic pathways that are uniquely altered in cancer and how these changes contribute to the disease's progression, offering potential targets for novel therapeutic interventions.
Both comprehensive reviews and original articles are welcome.
Dr. Michael Lisanti
Dr. Ubaldo Martinez-Outshoorn
Dr. Marta Mauro-Lizcano
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer
- metabolic reprogramming
- metabolic adaptation
- cancer energy metabolism
- glycolysis
- the Warburg effect
- the reverse Warburg effect
- glutamine addiction
- the pentose phosphate pathway
- cellular and molecular mechanisms
- tumor microenvironment
- novel therapeutic interventions
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
