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Chemosensors
Special Issues
Advanced Glucose Biosensors
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Advanced Glucose Biosensors

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "(Bio)chemical Sensing".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 3353

Special Issue Editor

Dr. Gabriela Valdés-Ramírez

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Guest Editor
Chemistry Department, Universidad Autónoma Metropolitana-Unidad Iztapalapa, Iztapalapa, Mexico
Interests: electrochemical biosensors; glucose; metabolites; wearable sensors; polymers; optical sensors; nanomaterials

Special Issue Information

Dear Colleagues,

The introduction of the first glucose biosensor arose several decades ago, and since then, several improvements have occurred. Glucose biosensors have been applied to clinical and alimentary fields. In the clinical field, their use began with blood and urine glucose monitoring in diabetic patients. Nowadays, glucose monitoring has been extended to ISF, tears, saliva, as well as human perspiration. Glucose monitoring has been essential to control and prevent diabetes complications, improving quality healthcare.

Throughout the development of glucose biosensors, different materials, nanomaterials, mediators, substrates, and enzymes, have been employed. The progress of biosensors has grown together with technological innovations, and currently, minimally invasive and non-invasive glucose biosensors can be found on the market.

Improvement is the goal of several research groups; for this Special Issue, we hope to collect papers that contribute to the field of advancing glucose biosensors, with original contributions full papers, communications, and review articles in the following areas:

  • Electrochemical glucose biosensors; 
  • Optical glucose biosensors;
  • Wearable glucose biosensors;
  • Strip glucose biosensors;
  • Saliva glucose biosensors;
  • Tears glucose biosensors; 
  • ISF glucose biosensors;
  • Glucose continuos monitoring;
  • Glucose biomediacal aplications.

Dr. Gabriela Valdés-Ramírez
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • electrochemical glucose biosensors
  • optical glucose biosensors
  • wearable glucose biosensors
  • strip glucose biosensors
  • saliva glucose biosensors
  • tears glucose biosensors
  • ISF glucose biosensors
  • glucose continuos monitoring
  • glucose biomediacal aplications

Published Papers (2 papers)

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16 pages, 4841 KiB  
Article
Non-Enzymatic Electrochemical Sensing of Glucose with a Carbon Black/Polyaniline/Silver Nanoparticle Composite
by Claudia Ivone Piñón-Balderrama, Claudia Alejandra Hernández-Escobar, Simón Yobanni Reyes-López, Alain Salvador Conejo-Dávila, Anayansi Estrada-Monje and Erasto Armando Zaragoza-Contreras
Chemosensors 2024, 12(2), 26; https://doi.org/10.3390/chemosensors12020026 - 09 Feb 2024
Viewed by 1214
Abstract
The present work describes the synthesis of an electroactive nanocomposite consisting of carbon black (CB) and polyaniline (PANI) obtained by in situ oxidative polymerization. Monomer P1 was used as a polyaniline precursor. P1 has surfactant properties that allow obtaining core–shell structures dispersed in [...] Read more.
The present work describes the synthesis of an electroactive nanocomposite consisting of carbon black (CB) and polyaniline (PANI) obtained by in situ oxidative polymerization. Monomer P1 was used as a polyaniline precursor. P1 has surfactant properties that allow obtaining core–shell structures dispersed in an aqueous medium. The nanocomposite, together with silver nanoparticles (AgNPs) as an electrocatalytic element, was used to modify the surface of a glassy carbon electrode (GCE) for glucose detection. Electroactive areas were calculated using the Randles–Sevick equation. The results showed that the CB-PANI.1-1/AgNP nanocomposite exhibited a larger electroactive surface area (0.3451 cm2) compared to AgNP alone (0.0973 cm2) or the CB-PANI.1-1 composite (0.2989 cm2). Characterization of CB-PANI.1-1/AgNP, by cyclic voltammetry in the presence of glucose, showed a new oxidation peak with a maximum current close to 0.7 V due to the oxidation of glucose to gluconolactone. The amperometry test at 0.7 V showed a linear response with R2 of 0.999 as a function of the analyte concentration. The glucose sensor presented a linear detection range of 1 to 10 mM, a sensitivity of 41 µA mM−1 cm−2, and a limit of detection (LOD) of 520 µM. Full article
(This article belongs to the Special Issue Advanced Glucose Biosensors)
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13 pages, 5348 KiB  
Article
Glucose Oxidase Captured into Electropolymerized p-Coumaric Acid towards the Development of a Glucose Biosensor
by Gabriela Valdés-Ramírez and Laura Galicia
Chemosensors 2023, 11(6), 345; https://doi.org/10.3390/chemosensors11060345 - 14 Jun 2023
Cited by 2 | Viewed by 1432
Abstract
An electrochemical biosensor based on the immobilization of glucose oxidase into an electropolymerized p-coumaric acid membrane on a Pt electrode has been developed and evaluated for glucose detection in the range of 1 to 30 mM. The glucose biosensor exhibits a sensitivity [...] Read more.
An electrochemical biosensor based on the immobilization of glucose oxidase into an electropolymerized p-coumaric acid membrane on a Pt electrode has been developed and evaluated for glucose detection in the range of 1 to 30 mM. The glucose biosensor exhibits a sensitivity of 36.96 mA/mMcm2, a LOD of 0.66 mM, and a LOQ of 2.18 mM. The biosensing membrane was electropolymerized by cyclic voltammetry in 100 mM phosphates pH 7.00 and 3% ethanol containing glucose oxidase and p-coumaric acid. The glucose biosensors’ stability, repeatability, reproducibility, and selectivity were estimated. The biosensing membrane shows permselective properties and antifouling effects. The applicability of the developed glucose biosensor was evaluated in the presence of 20 mg/mL proteins, and any signal associated with biofouling was observed. The glucose biosensors were employed for the determination of the glucose concentration in three commercial beverages. Full article
(This article belongs to the Special Issue Advanced Glucose Biosensors)
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