Protein Domains: Structure and Molecular Function
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Biochemistry, Molecular and Cellular Biology".
Deadline for manuscript submissions: 31 October 2024 | Viewed by 1124
Special Issue Editor
Special Issue Information
Dear Colleagues,
Protein domains, which are unique autonomous folding units, possess distinct structural and functional characteristics. These domains typically determine a protein’s biological role by contributing to a specific function or interaction. The identification of these protein domains is often a crucial step in understanding the structure and function of the protein.
Over the past decades, a variety of experimental and computational techniques have been developed and utilized to identify and characterize protein domains. These techniques include X-ray crystallography, cryo-electron microscopy (cryo-EM), and molecular dynamics simulations. In recent years, deep learning models have emerged as powerful tools in this field. They have been particularly effective in predicting domain boundaries and functions based on sequence and structure information.
Furthermore, protein domains can serve as essential building blocks in protein engineering, allowing for the design of proteins with desired functions. This capability has significant implications for various fields, including drug design and synthetic biology.
This Special Issue of CIMB welcomes both original research and comprehensive review papers on the study of the molecular structure and function of protein domains. We look forward to receiving your contributions.
Dr. Guangfeng Zhou
Guest Editor
Manuscript Submission Information
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Keywords
- protein structure
- protein domains
- domain classification
- protein engineering
- protein design
- protein modeling
- machine learning
- deep learning
- protein structure prediction
- protein function prediction
