Network Pharmacology, Multi-targets and Receptor–Receptor Interactions in the CNS
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 2466
Special Issue Editors
Interests: neuroscience; neurotransmitters and gliotransmitters; exosomes; glial cells; receptor heterodimerization
Interests: Alzheimer’s disease, animal behaviour, receptor-receptor interaction, nicotinic receptors, muscarinic receptors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Network pharmacology, multi-targets and receptor–receptor interactions in the CNS are three keys to future drug therapy in CNS.
Recent advances have highlighted the limitations of the traditional 'one-to-one' therapeutic approach, where a single molecule targets a specific protein in the central nervous system (CNS). As in vitro and in vivo techniques have improved, we have gained a deeper understanding of the intricate network of interactions among target proteins. This dynamic interplay requires a comprehensive assessment of the physiological and pathological conditions that may influence these interactions. To address these challenges, modern approaches such as network pharmacology, multi-targeting, and receptor–receptor interactions offer promising solutions. This Special Issue aims to integrate information from articles and reviews focusing on topics such as:
- Network pharmacology in the CNS;
- Polypharmacology in the CNS;
- Multi-targets in the CNS;
- Phytocomplexes and pharmacological activities in the CNS;
- Receptor–receptor interactions in the CNS;
- Crosstalk in the CNS.
Dr. Chiara Cervetto
Dr. Massimo Grilli
Guest Editors
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Keywords
- network pharmacology
- multi-targets
- receptor–receptor interactions
- target proteins
- drug therapy in CNS
- receptors
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