Signaling Pathways, Development, and Biomarkers in Neuropathy
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 20999
Special Issue Editors
Interests: neuropathic pain; subarachnoid hemorrhage; peripheral nerve injury; spinal cord injury; traumatic brain injury; neurosurgery
Special Issues, Collections and Topics in MDPI journals
Interests: neuropathic pain; subarachnoid hemorrhage; nerve repair; brain tumor; neuroinflammation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neuropathy is damage or dysfunction of one or more nerves that typically results in numbness, tingling, muscle weakness and pain. In addition, neuro-inflammation plays an important role in the course of chronic sciatic injury. Inflammatory factors at damaged nerves stimulate excessive activation of glial cells, which then causes neuropathic pain. Molecular mechanisms that underlie the sensitization of primary afferent nociceptors include upregulation of voltage-gated sodium channels and various receptor proteins, and the release of growth factors from degenerating nerve fibers. Therefore, molecular therapy is an important role on neuropathy. The aim of this Special Issue to highlight researcher’s recent significant pilot or meta-analysis results related to therapy in neuropathy including gene therapy, potential biomarker, and signal pathway.
Prof. Dr. Aij Lie Kwan
Dr. Hung-Pei Tsai
Guest Editors
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Keywords
- pain
- peripheral nerve injury
- spinal cord injury
- neuro-inflammation
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