microRNA Expression and Detection in COVID-19 and Long COVID Conditions

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: closed (28 February 2023) | Viewed by 3353

Special Issue Editors


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Guest Editor
1. Anaesthesia and Intensive Care Department, Faculty of Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania
2. Clinic of Anaesthesia and Intensive Care, Emergency County Hospital "Pius Brinzeu", Timisoara, Romania
3. Medical Education and Clinical Research Department, Romanian Society of Anesthesia and Intensive Care, Bucharest, Romania
Interests: critical care; anaesthesia; biochemistry; molecular pathways
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. Anaesthesia and Intensive Care Department, Faculty of Medicine, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
2. Clinic of Anaesthesia and Intensive Care, Emergency County Hospital “Pius Brinzeu”, Timisoara, Romania
3. Medical Education and Clinical Research Department, Romanian Society of Anesthesia and Intensive Care, Bucharest, Romania
Interests: anaesthesia; intensive care; antibiotics; biochemistry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The health crisis generated by the COVID-19 pandemic represented a real challenge for all of humanity. Shortly after the identification of the first infections with the new SARS-CoV-2 coronavirus, a series of modern rapid identification techniques were developed and researched, the main goal being the mass testing of the population in order to identify and isolate to reduce transmission.

An intensively studied segment was represented by the expression of microRNAs both in the identification/testing methods and in the development of vaccines and the detailed understanding of the biochemical and molecular processes that take place in COVID-19 patients.

We are pleased to invite you to contribute with papers in this Special Issue regarding the expression of microRNAs in COVID-19, the use of microRNAs in the detection of SARS-CoV-2, the use of microRNAs in the development of innovative treatments for patients with COVID-19, and the interaction of microRNAs in the pathways biochemical and molecular specific to this pathology.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • microRNA expression in COVID-19;
  • Use of microRNAs in the detection of SARS-CoV-2;
  • Implications of microRNAs in the biochemical pathways of COVID-19;
  • Expression of microRNAs in the inflammatory response in COVID-19 patients;
  • Other clinical and biochemical complications specific to COVID-19;
  • Impact of COVID-19 on public health.

We look forward to receiving your contributions.

Dr. Alexandru Florin Rogobete
Prof. Dr. Dorel Sandesc
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • COVID-19
  • SARS-CoV-2
  • biomarkers
  • microRNA expression
  • inflammation
  • COVID-19 pandemic crisis

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Published Papers (1 paper)

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Review

16 pages, 754 KiB  
Review
miRNAs as a Potential Biomarker in the COVID-19 Infection and Complications Course, Severity, and Outcome
by Milena Jankovic, Dejan Nikolic, Ivana Novakovic, Bojana Petrovic, Milan Lackovic and Milena Santric-Milicevic
Diagnostics 2023, 13(6), 1091; https://doi.org/10.3390/diagnostics13061091 - 14 Mar 2023
Cited by 8 | Viewed by 2827
Abstract
During the last three years, since the emergence of the COVID-19 pandemic, a significant number of scientific publications have focused on resolving susceptibility to the infection, as well as the course of the disease and potential long-term complications. COVID-19 is widely considered as [...] Read more.
During the last three years, since the emergence of the COVID-19 pandemic, a significant number of scientific publications have focused on resolving susceptibility to the infection, as well as the course of the disease and potential long-term complications. COVID-19 is widely considered as a multisystem disease and a variety of socioeconomic, medical, and genetic/epigenetic factors may contribute to the disease severity and outcome. Furthermore, the SARS-COV-2 infection may trigger pathological processes and accelerate underlying conditions to clinical entities. The development of specific and sensitive biomarkers that are easy to obtain will allow for patient stratification, prevention, prognosis, and more individualized treatments for COVID-19. miRNAs are proposed as promising biomarkers for different aspects of COVID-19 disease (susceptibility, severity, complication course, outcome, and therapeutic possibilities). This review summarizes the most relevant findings concerning miRNA involvement in COVID-19 pathology. Additionally, the role of miRNAs in wide range of complications due to accompanied and/or underlying health conditions is discussed. The importance of understanding the functional relationships between different conditions, such as pregnancy, obesity, or neurological diseases, with COVID-19 is also highlighted. Full article
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