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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Integrated Assessment and Management of Heart Failure Syndromes

edited by Damiano Magrì and Emiliano Fiori

submission deadline 30 Jul 2026 | Viewed by 2450 | Submission Open

Keywords: heart failure; functional capacity; multimodality assessment; advanced imaging; coronary and structural interventions; device therapies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Essentials of Imaging Diagnosis in Pulmonary Diseases: Techniques and Clinical Practice

edited by Chiara Romei

submission deadline 30 Jul 2026 | 1 articles | Viewed by 2279 | Submission Open

Keywords: pulmonary imaging; CT, MRI, and PET/CT imaging for lung diseases; quantitative imaging; artificial intelligence and machine learning; ventilation and perfusion imaging; clinical application; diagnosis; personalized medicine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advancements in Artificial Intelligence for Dentomaxillofacial Radiology—2nd Edition

edited by

Andre Luiz Ferreira Costa

Kaan Orhan

and

Sérgio Lúcio Pereira de Castro Lopes

submission deadline 31 Jul 2026 | 10 articles | Viewed by 31233 | Submission Open

Keywords: artificial intelligence; deep learning; dentomaxillofacial radiology; dentistry; diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Sarcoidosis: From Diagnosis to Management

edited by Huzaifa I. Adamali

submission deadline 31 Jul 2026 | 5 articles | Viewed by 20983 | Submission Open

Keywords: sarcoidosis; granulomas; interstitial lung disease; lung; heart; skin; liver; neurological; joints; diagnosis imaging; PET/CT; chest X-ray

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Frontline of Breast Imaging

edited by

Gary J. Whitman

submission deadline 31 Jul 2026 | 8 articles | Viewed by 16589 | Submission Open

Keywords: breast imaging; breast ultrasound; mammography; digital breast tomosynthesis; digital mammography; contrast-enhanced mammography; breast MRI; molecular breast imaging; imaging-guided interventional breast procedures

(This special issue belongs to the Section Medical Imaging and Theranostics)

Skin and Cutaneous Adnexal Tumors: Diagnosis and Management—2nd Edition

edited by

Andreas Manios

and

Dimitra Koumaki

submission deadline 31 Jul 2026 | 4 articles | Viewed by 14041 | Submission Open

Keywords: cutaneous adnexal tumors; follicular and sebaceous tumors; sweat gland tumors

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Gastrointestinal Endoscopy: From Diagnosis to Therapy

edited by Cristiano Spada and Daniele Salvi

submission deadline 31 Jul 2026 | 8 articles | Viewed by 12281 | Submission Open

Keywords: gastrointestinal endoscopy; therapeutic endoscopy; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); artificial intelligence; small bowel capsule endoscopy; bariatric endoscopy

(This special issue belongs to the Section Biomedical Optics)

Advances in Mental Health Diagnosis and Screening, 2nd Edition

edited by Elaine Chapman

submission deadline 31 Jul 2026 | 8 articles | Viewed by 10838 | Submission Open

Keywords: mental health; diagnosis; screening; marker; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Updates on Stroke: Diagnosis and Management

edited by Joseph Domenico Gabrieli

submission deadline 31 Jul 2026 | 3 articles | Viewed by 10755 | Submission Open

Keywords: ischemic stroke; atheromatous disease; thrombolysis; machine learning; neurovascular anatomy; imaging; thrombectomy; diagnosis and management; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Echocardiography Applications in Cardiovascular Diseases

edited by

Corina Maria Vasile

submission deadline 31 Jul 2026 | 5 articles | Viewed by 10527 | Submission Open

Keywords: echocardiography; congenital heart disease; imaging techniques; artificial intelligence; automatization

(This special issue belongs to the Section Medical Imaging and Theranostics)

Large Language Models in Medical Diagnostics: Advancing Clinical Practice, Research, and Patient Care

edited by

Tim Duong

submission deadline 31 Jul 2026 | 8 articles | Viewed by 10441 | Submission Open

Keywords: large language models; diagnostic; prognosis; decision support; clinical practice

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Bacterial Infections and Antimicrobial Resistance: Diagnosis and Management

edited by

Georgina Tzanakaki

submission deadline 31 Jul 2026 | 7 articles | Viewed by 10183 | Submission Open

Keywords: bacterial infections; antimicrobial resistance (AMR); diagnostic innovations; molecular diagnostics; antimicrobial stewardship; multidrug-resistant pathogens; alternative therapies; artificial intelligence

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Imaging of the Future: From the Standardisation of Diagnostic Processes to Artificial Intelligence

edited by

Emanuele David

submission deadline 31 Jul 2026 | 3 articles | Viewed by 8635 | Submission Open

Keywords: artificial intellicence; technologies; ultrasound; MRI; CT; angiography; mammography

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Imaging in Neurological Diseases: 2nd Edition

edited by

Daniele Coraci

submission deadline 31 Jul 2026 | 2 articles | Viewed by 7958 | Submission Open

Keywords: diagnostic imaging; neurological diseases/disorders; central nervous system; imaging techniques; magnetic resonance imaging (MRI); positron emission tomography (PET); diagnostic modalities

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Breast Cancer Imaging 2026

edited by Takouhie Catherine Maldjian

submission deadline 31 Jul 2026 | 5 articles | Viewed by 6490 | Submission Open

Keywords: breast cancer; neoadjuvant chemotherapy; axillary lymph nodes; molecular subtypes; hormonal receptor positive; medical oncology; breast surgery; breast cancer metastasis; pathological complete response; breast cancer recurrence clinical impact and innovation; diagnostic; prognosis; markers; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Imaging for the Diagnosis of Obstetric and Gynecological Diseases—2nd Edition

edited by

Nicolae Gica

submission deadline 31 Jul 2026 | 5 articles | Viewed by 6268 | Submission Open

Keywords: diagnosis; imaging; gynecology and obstetrics; gynecological cancer; hysteroscopy; ovarian disease

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Cardiothoracic and Abdominal Imaging: From CT Innovations to AI Diagnostics

edited by

Tommaso D'Angelo

submission deadline 31 Jul 2026 | 3 articles | Viewed by 5606 | Submission Open

Keywords: cardiothoracic imaging; abdominal imaging; CT technologies; artificial intelligence (AI) in diagnosis; AI-based imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Future Trends in Diagnostic and Interventional Radiology

edited by

Francesco Giurazza

submission deadline 31 Jul 2026 | 3 articles | Viewed by 5379 | Submission Open

Keywords: diagnostic radiology; interventional radiology; medical imaging; artificial intelligence; minimally invasive therapy; radiomics; precision medicine; multidisciplinary research

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Diagnostic Approaches in Uveitis and Inflammatory Vitreoretinal Diseases

edited by

Dimitrios Kalogeropoulos

submission deadline 31 Jul 2026 | 4 articles | Viewed by 5347 | Submission Open

Keywords: uveitis; inflammatory retinal disease; multimodal imaging; OCTA; imaging biomarkers; vitreous diagnostics; aqueous humor analysis; cytokine profiling; intraocular inflammation; infectious and non-infectious uveitis; AI in imaging; personalized diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Subjective Experiences of Decline and Dementia Risk: Cognitive, Functional, and Emotional Predictors of Cognitive Decline

edited by Katya Numbers

submission deadline 31 Jul 2026 | 3 articles | Viewed by 5147 | Submission Open

Keywords: subjective cognitive decline (SCD); dementia risk; cognitive complaints; functional decline; emotional well-being; early diagnosis and intervention

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Insights into Emergency Medicine

edited by Evan Avraham Alpert

submission deadline 31 Jul 2026 | 2 articles | Viewed by 4669 | Submission Open

Keywords: emergency medicine; trauma; sepsis; acute coronary syndrome; mortality

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

New Advances in Retinal Imaging

edited by

Rodolfo Mastropasqua

and

Maria Ludovica Ruggeri

submission deadline 31 Jul 2026 | 1 articles | Viewed by 4638 | Submission Open

Keywords: retina; vitreoretinal diseases; inherited retinal dystrophies; diabetic retinopathy; age-related macular degeneration; retinal detachment; optical coherence tomography; imaging

(This special issue belongs to the Section Biomedical Optics)

Recent Advances in the Diagnosis and Management of Gynecological Cancers

edited by Zelal M. Muallem

submission deadline 31 Jul 2026 | 4 articles | Viewed by 4014 | Submission Open

Keywords: gynecological cancers; diagnosis and staging; molecular biomarkers; targeted therapies; immunotherapy; minimally invasive surgery; personalized medicine; cancer resistance; quality of life in oncology; disparities in cancer care

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Neonatal Diagnostics

edited by

Yogen Singh

submission deadline 31 Jul 2026 | 1 articles | Viewed by 3593 | Submission Open

Keywords: neonatal imaging; point-of-care ultrasound (POCUS); targeted neonatal echocardiography; hemodynamic evaluation; functional MRI (fMRI); diffusion tensor imaging (DTI); genomic testing; neonatal intensive care units (NICUs)

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Emerging Technologies and Diagnostic Innovations in Optometry and Vision Science

edited by

Shuan-Yu Huang

submission deadline 31 Jul 2026 | 4 articles | Viewed by 3494 | Submission Open

Keywords: optometry; vision diagnostics; ocular imaging; binocular vision; accommodation–vergence; AI in eye care; visual training; digital theranostics; sports vision; VR/AR; smart medical devices

(This special issue belongs to the Section Biomedical Optics)

Advanced Imaging in the Diagnosis and Management of Skin Diseases

edited by Lehang Guo

submission deadline 31 Jul 2026 | 5 articles | Viewed by 3397 | Submission Open

Keywords: skin diseases; ultrasound imaging; optical coherence tomography (OCT) imaging; photoacoustic imaging; reflectance confocal microscopy (RCM) imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnosis and Treatment in Pediatric Dentistry

edited by

Patrizia Gallenzi

Edoardo Staderini

and Federica Guglielmi

submission deadline 31 Jul 2026 | 1 articles | Viewed by 3237 | Submission Open

Keywords: OSA; special needs patients; interceptive orthodontics; proteomics; 3D imaging; parafunctional habits

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Gynecological Disorders

edited by

Yasushi Kotani

submission deadline 31 Jul 2026 | 3 articles | Viewed by 3165 | Submission Open

Keywords: gynecological diseases; diagnosis; management strategies; obstetrics and gynecology; women’s health; clinical practice guidelines; reproductive health disorders

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Imaging and Theranostics in Neurological Diseases

edited by

Jimmy S. Lee

submission deadline 31 Jul 2026 | 5 articles | Viewed by 3070 | Submission Open

Keywords: neuroradiology; MRI; PET-MRI; neurology and neurosurgery; imaging; theranostics; diagnostic; prognosis; markers

(This special issue belongs to the Section Medical Imaging and Theranostics)

Deep Learning in Medical Imaging: Challenges and Opportunities

edited by Morten Bo Søndergaard Svendsen

submission deadline 31 Jul 2026 | 1 articles | Viewed by 3004 | Submission Open

Keywords: deep learning; artificial intelligence; medical imaging; endoscopy; image segmentation; medical image processing

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Clinical Anatomy: Morphometric Analysis and Diagnostic Relevance

edited by

Jae-Ho Lee

and

Kwang-Rak Park

submission deadline 31 Jul 2026 | 4 articles | Viewed by 2993 | Submission Open

Keywords: clinical anatomy; morphometric analysis; anatomical variation; computed tomography three-dimensional reconstruction; diagnostic anatomy; applied anatomy; evidence-based anatomy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Ultrasound in the Diagnosis and Management of Skin Diseases—2nd Edition

edited by

Joanna Czajkowska

Norbert Kiss

and Miklós Gyöngy

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2619 | Submission Open

Keywords: skin diseases; ultrasound; skin cancer; machine learning; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Risk Factors for Frailty in Older Adults: Second Edition

edited by

Agustín Aibar Almazán

and

María del Carmen Carcelén-Fraile

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2503 | Submission Open

Keywords: frailty; older adults; risk factors; mental health; physical function; cognition; multidimensional intervention; frailty screening; quality of life; sleep quality

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Emergency and Critical Illness

edited by

Yi Li

submission deadline 31 Jul 2026 | 3 articles | Viewed by 2269 | Submission Open

Keywords: emergency medicine; critical illness; rapid diagnosis; sepsis; acute cardiac events; acute abdomen; traumatic injuries; clinical toxicology; clinical images; biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Novel Insights and Technological Advances in Neuroimmunology and Neuroinflammation

edited by Hongzhi Guan

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1988 | Submission Open

Keywords: neuroimmunology; neuroinflammation; autoimmune; encephalitis; infection; diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Current Status and Challenges of Heart Disease Diagnosis

edited by

Giuseppe Sgarito

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1738 | Submission Open

Keywords: heart disease; cardiovascular diagnosis; cardiac imaging; artificial intelligence; biomarkers; end-stage heart failure; electrophysiology; sudden cardiac death; tissue characterization; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Precision Diagnostics in Kidney Cancer

edited by

Qiang Lv

, Xiao Yang and Qiang Cao

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1647 | Submission Open

Keywords: renal tumor; diagnostic and prognostic markers; non-invasive; artificial intelligence; precision diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Nephrology: Diagnosis and Management, Second Edition

edited by Elio Antonucci

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1126 | Submission Open

Keywords: kidney disease; nephropathy; diagnosis; renal disease; pathophysiology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Challenges in the Diagnosis and Treatment of Cardiac and Respiratory Infections

edited by

Alessandro Russo

and Francesca Serapide

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1114 | Submission Open

Keywords: cardiac infections; respiratory infections; diagnostic challenges; antimicrobial resistance; biomarkers; molecular diagnostics; targeted therapies; cardiopulmonary disease

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

New Advances in the Diagnosis of Pediatric Diseases

edited by Mariapina Cerulo

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1088 | Submission Open

Keywords: pediatric diseases diagnostic; artificial intelligence-assisted diagnostics; non-invasive diagnostic methodologies; early detection and disease stratification in children; precision medicine approaches in pediatrics; diagnostic biomarkers for pediatric disorders

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Morbid Obesity

edited by Justyna Domienik-Karłowicz

submission deadline 31 Jul 2026 | 1 articles | Viewed by 993 | Submission Open

Keywords: morbid obesity; obesity diagnosis; body composition analysis; visceral adiposity; metabolic syndrome; biomarkers in obesity; genetic predisposition; comorbidity assessment; imaging techniques; risk stratification

(This special issue belongs to the Section Medical Imaging and Theranostics)

Emerging Technologies in Breast Imaging

edited by

Yufeng Zhou

submission deadline 31 Jul 2026 | 1 articles | Viewed by 975 | Submission Open

Keywords: ultrafast ultrasound; photon-counting CT; abbreviated MRI; optoacoustic tomography; contrast-enhanced mammography; PEM; breast PET/MRI; radiomics; deep-learning reconstruction; cone-beam CT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnostic and Interventional Nephrology

edited by Ammar Almehmi

submission deadline 31 Jul 2026 | 1 articles | Viewed by 922 | Submission Open

Keywords: dialysis access; fistula; graft; stent; peritoneal catheter; drug-coated balloon; EndoAVF; dialysis; vascular access dysfunction; interventional nephrology; diagnostic imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Insights into Molecular Diagnostic Technologies

edited by Hin Fung Tsang

submission deadline 31 Jul 2026 | Viewed by 824 | Submission Open

Keywords: molecular diagnostics; advanced technologies; disease diagnosis; disease monitoring; disease management; personalized medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Images in the Diagnosis of Macular Edema, Second Edition

edited by

Gawęcki Maciej

submission deadline 31 Jul 2026 | 1 articles | Viewed by 787 | Submission Open

Keywords: macular edema; diagnostic imaging; optical coherence tomography (OCT); fluorescein angiography; retinal imaging techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in the Service of Medicine: From Pathological Diagnosis to Forensic Pathology

edited by

Gelsomina Mansueto

submission deadline 31 Jul 2026 | 1 articles | Viewed by 693 | Submission Open

Keywords: artificial intelligence in pathology; digital pathology; computational pathology; whole-slide imaging (WSI); machine learning-based diagnostics; deep learning algorithms; pathology; cardiopathology; neuropathology; forensic pathology; postmortem imaging analysis; biomarker detection and quantification

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Markers of Genitourinary Tumors: 2nd Edition

edited by

Francesca Sanguedolce

and

Roberta Mazzucchelli

submission deadline 31 Jul 2026 | Viewed by 667 | Submission Open

Keywords: genitourinary tumors; diagnostic markers; biomarkers; molecular diagnostics; personalized medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis of Surgical Pathology

edited by Dong Ren

submission deadline 31 Jul 2026 | Viewed by 640 | Submission Open

Keywords: pathological diagnosis; diagnostic dilemma and pitfall; molecular pathology; digital pathology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Application of Artificial Intelligence in Gastrointestinal Disease, 2nd Edition

edited by

Kai Zhao

submission deadline 31 Jul 2026 | 1 articles | Viewed by 544 | Submission Open

Keywords: artificial intelligence; machine learning; gastrointestinal disease

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Image Guided Neurointerventional Surgery: Focus on Diagnosis and Outcomes

edited by Dheeraj Gandhi and Huanwen Chen

submission deadline 31 Jul 2026 | Viewed by 405 | Submission Open

Keywords: image guided neurointerventional surgery; diagnosis; outcomes; computed tomography (CT); magnetic resonance imaging (MRI)

(This special issue belongs to the Section Medical Imaging and Theranostics)

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