Advances in Sarcopenia: Predictive Biomarkers, Clinical Characteristics, and Therapeutic Strategies

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 525

Special Issue Editor


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Guest Editor
Department of Physical and Rehabilitation Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea
Interests: musculoskeletal diseases; electrodiagnostic medicine; spinal cord injury; intensive care unit rehabilitation; respiratory rehabilitation; sarcopenia

Special Issue Information

Dear Colleagues,

This Special Issue seeks to explore the advancements in the understanding, diagnosis, and treatment of sarcopenia, focusing on the integration of predictive biomarkers, clinical characteristics, and innovative therapeutic strategies. By compiling research on biochemical and physiological biomarkers, this Special Issue aims to determine the pathways through which the biomarkers of sarcopenia can be predicted and monitored more effectively. In addition to traditional clinical observations, we encourage submissions that utilize advanced imaging techniques, biometric analyses, and computational modeling to refine the clinical profiles associated with sarcopenia.

We also aim to highlight therapeutic advances, ranging from pharmacological interventions to non-invasive therapies that employ digital health technologies. The scope of this Special Issue extends to interdisciplinary approaches that combine nutrition and rehabilitation to offer comprehensive treatment. Through a collaborative exploration of these themes, this Special Issue will provide a platform for researchers to share insights and propose innovative solutions that address the global challenge of sarcopenia in aging populations. This Special Issue will serve as a crucial resource for clinicians and researchers involved in the management of sarcopenia.

Dr. Jong Geol Do
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sarcopenia
  • predictive biomarkers
  • digital health technologies
  • interdisciplinary treatment approaches
  • aging population management

Published Papers (1 paper)

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Research

12 pages, 1728 KiB  
Article
Effects of Intra-Articular Triamcinolone Injection on Adhesive Capsulitis after Breast Cancer Surgery
by Sungwon Kim, Sunwoo Kim, Jong Geol Do and Ji Hye Hwang
Diagnostics 2024, 14(14), 1464; https://doi.org/10.3390/diagnostics14141464 - 9 Jul 2024
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Abstract
Purpose: To investigate the effects of intra-articular glenohumeral joint triamcinolone injection in treating secondary adhesive capsulitis after breast cancer surgery. Methods: This study prospectively enrolled 37 participants, including 22 in the breast cancer surgery group and 15 in the idiopathic group. All participants [...] Read more.
Purpose: To investigate the effects of intra-articular glenohumeral joint triamcinolone injection in treating secondary adhesive capsulitis after breast cancer surgery. Methods: This study prospectively enrolled 37 participants, including 22 in the breast cancer surgery group and 15 in the idiopathic group. All participants received intra-articular glenohumeral joint triamcinolone injection in the affected shoulder joint. The clinical outcomes included the Shoulder Pain and Disability Index (SPADI), passive range of motion (PROM), and pain intensity on the Numeric Rating Scale (NRS), which were evaluated before the intervention and 1, 3, and 6 months after. The primary outcome of this study was the mean difference in the total SPADI from baseline to 6 months after the intervention. Results: The mean differences in the total SPADI scores from baseline to 6 months after the intervention were 36.2 ± 16.4 and 47.9 ± 15.2 in the breast cancer surgery group and the idiopathic group, respectively. There was no significant difference between the two groups (p = 0.1495). However, the improvements in the SPADI pain subscale at the 3- and 6-month follow-up visits (−31.2 vs. −48.8, p = 0.042; −34.1 vs. −50.7, p = 0.0006) and the PROM of abduction at the 3-month follow-up (52.4 vs. 70.3, p = 0.0072) were inferior in the breast cancer surgery group compared to the idiopathic group. There were no adverse events in either group. Conclusion: Intra-articular triamcinolone injection is an effective and safe treatment option for adhesive capsulitis after breast cancer surgery; however, it has less effect than for idiopathic adhesive capsulitis. Full article
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