Diagnostic Probes
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Point-of-Care Diagnostics and Devices".
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 5457
Special Issue Editor
Interests: nucleic acids; diagnostics; biosensors; bioregnition molecules; nucleases; targeted strategies; personalized medicine; oligonucleotide synthesis and modifications
Special Issue Information
Dear Colleagues,
Diagnosis is a critical process that identifies the cause of a disease and facilitates the appropriate therapeutic treatment. Thus, diagnosis is the key factor for patient care, experimental research, and healthcare policy. In the last decades, innovation and breakthroughs in diagnostics have shown a plethora of approaches based on the understanding at the molecular level. With the advent of PCR, the molecular diagnosis has played an important role in the diagnostic field. However, the amplification methods based on PCR are not the only option for developing diagnostic probes based on nucleic acids. Interesting approaches, such as the development of biosensors using the hybridization features of nucleic acids, have been successfully explored. Likewise, nucleic acid aptamers have shown their great potential in diagnostics, in this case, using the 3D conformational capabilities of nucleic acids to create recognition molecules similar to antibodies. Another approach uses nucleic acids as substrates for the recognition of nucleases as target biomarkers of disease. This strategy takes advantage of the diversity and variability of nucleases to create substrates with a high specificity and sensitivity for a given nuclease. Thus, nucleic acids offer great flexibility and versatility for designing novel diagnostic probes, and they will most likely lead the diagnostic field in the future.
In this Special Issue, we will focus on the nucleic acid diagnostic probes based on amplification, hybridization, aptamers, and nucleic acid substrates.
Dr. Frank J. Hernandez
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
