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Diagnostics
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Advances in the Diagnosis and Management of Vasculitis
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Advances in the Diagnosis and Management of Vasculitis

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 1058

Special Issue Editor

Dr. Alicia Rodríguez-Pla

E-Mail Website
Guest Editor
Sierra Pacific Arthritis and Rheumatology Centers, Visalia, CA, USA
Interests: vasculitis; scleroderma; IgG4-related disease

Special Issue Information

Dear colleagues, 

Research in the field of primary systemic vasculitides is an evolving topic. Advances in their diagnosis and management are quickly improving patient outcomes. In recent years, less invasive imaging studies have become available to assist with the diagnosis and treatment guidance of vasculitis, especially for those with large-vessel involvement. Advances in the understanding of immunopathogenesis, the search for biomarkers, the increased recognition of steroids’ toxicity, and the increased interest in clinical trials have advanced the use of targeted therapies that have revolutionized the management of vasculitides. To keep up with these advances, this Special Issue is dedicated to updates on the diagnosis and management of primary systemic vasculitides. Proposals in agreement with this broad topic are welcome. In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: imaging studies on vasculitis, biomarkers, treatment approaches, patient outcomes, and epidemiologic studies.

We look forward to receiving your contributions.

Dr. Alicia Rodríguez-Pla
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • vasculitis
  • advances
  • updates
  • management
  • treatment
  • therapy

Published Papers (2 papers)

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Review

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15 pages, 1013 KiB  
Review
Positron Emission Tomography/Computed Tomography in Polymyalgia Rheumatica: When and for What—A Critical Review
by Elena Heras-Recuero, Teresa Blázquez-Sánchez, Laura Cristina Landaeta-Kancev, Marta Martínez de Bourio-Allona, Arantxa Torres-Roselló, Fernando Rengifo-García, Claritza Caraballo-Salazar, Raquel Largo, Santos Castañeda and Miguel Ángel González-Gay
Diagnostics 2024, 14(14), 1539; https://doi.org/10.3390/diagnostics14141539 - 17 Jul 2024
Viewed by 144
Abstract
Polymyalgia rheumatica (PMR) is an inflammatory disease common in people aged 50 years and older. This condition is characterized by the presence of pain and stiffness involving mainly the shoulder and pelvic girdle. Besides the frequent association with giant cell arteritis (GCA), several [...] Read more.
Polymyalgia rheumatica (PMR) is an inflammatory disease common in people aged 50 years and older. This condition is characterized by the presence of pain and stiffness involving mainly the shoulder and pelvic girdle. Besides the frequent association with giant cell arteritis (GCA), several conditions may mimic PMR or present with PMR features. Since the diagnosis is basically clinical, an adequate diagnosis of this condition is usually required. Positron emission tomography/computed tomography (PET-CT) has proved to be a useful tool for the diagnosis of PMR. The use of 18F-FDG-PET imaging appears promising as it provides detailed information on inflammatory activity that may not be evident with traditional methods. However, since PET-CT is not strictly necessary for the diagnosis of PMR, clinicians should consider several situations in which this imaging technique can be used in patients with suspected PMR. Full article
(This article belongs to the Special Issue Advances in the Diagnosis and Management of Vasculitis)
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7 pages, 4416 KiB  
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Central Retinal Artery Occlusion Associated with Takayasu Arteritis
by Sehreen Mumtaz, Claire Wilson, Prasanna Vibhute, Eric R. Eggenberger, Florentina Berianu and Andy Abril
Diagnostics 2024, 14(13), 1329; https://doi.org/10.3390/diagnostics14131329 - 23 Jun 2024
Viewed by 472
Abstract
Takayasu arteritis is a chronic inflammatory vasculitis with granulomatous panarteritis particularly impacting large vessels including the aorta and its branches, especially the subclavian arteries, with clinical manifestation dependent on the involved artery. Sequelae of the active disease vary, including stenosis, occlusions, or aneurysmal [...] Read more.
Takayasu arteritis is a chronic inflammatory vasculitis with granulomatous panarteritis particularly impacting large vessels including the aorta and its branches, especially the subclavian arteries, with clinical manifestation dependent on the involved artery. Sequelae of the active disease vary, including stenosis, occlusions, or aneurysmal dilatations of the large vessels. The prevalence of Takayasu arteritis is higher in the Asian population and in Japan, but quite low in the United States, varying from 0.9–8.4 per million people. Ocular manifestations are rare and lead to a delay in diagnosis and appropriate treatment. Ocular manifestations include Takayasu retinopathy, anterior ischemic optic neuropathy (AION), retinal artery occlusion (RAO) and retinal vein occlusion (RVO). We present two cases in which central retinal artery occlusion (CRAO) was associated with Takayasu arteritis. CRAO is an ophthalmic emergency with an incidence of 1.9 per 100,000 person years in the United States; only 5% of cases are arteritic, which can be observed with inflammatory vasculitides secondary to the formation of immune deposits. Full article
(This article belongs to the Special Issue Advances in the Diagnosis and Management of Vasculitis)
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