State-of-the-Art Research of Pediatric Imaging

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 1839

Special Issue Editor


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Guest Editor
Pediatric Radiology Department, University of Brescia, Children Hospital of Brescia, Brescia, Italy
Interests: pediatric tumors; ultrasound; computed tomography; magnetic resonance imaging; interventional radiology

Special Issue Information

Dear Colleagues, 

This Special Issue of Diagnostics will focus on state-of-the-art literature reviews, as well as findings on the most frequent tumors of the thoracic, abdominal and skeletal region seen in children. It would be desirable to divide the various articles according to the lesions that can be found in the first year of life, in small children, in older children and in adolescents because it could be helpful reading for those who are less skilled in pediatric pathology. It is known that some neoplasms are more frequent in the first year of life and others in older children, and this can also help increase confidence in the histology of these tumors. In this Special Issue, works that correlate the various imaging techniques with surgical and histological data will also be particularly appreciated. With regard to imaging techniques, a greater space must be given for the description of methods that do not use ionizing radiation (i.e., ultrasound and magnetic resonance imaging). Computed tomography and nuclear medicine methods must be included in the diagnostic process. Lastly, works that highlight particular aspects of lesions not reported in the literature can also be considered, also in relation to the new histological reading methods related to the radiological data.

Dr. Maria Pia Bondioni
Guest Editor

Manuscript Submission Information

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Keywords

  • hepatoblastoma
  • hepatocellular carcinoma
  • fibrolamellar hepatocellular carcinoma
  • cholangiocarcinoma
  • undifferentiated embryonal sarcoma
  • biliary rhabdomyosarcoma
  • angiosarcoma
  • neuroblastoma
  • Wilm’s tumor
  • clear cell sarcoma of the kidney
  • malignant rhabdoid tumor of the kidney
  • congenital mesoblastic nephroma
  • renal cell carcinoma
  • Ewing sarcoma
  • osteosarcoma
  • bone lymphoma
  • histiocytosis
  • immunohistochemistry
  • molecular analysis. US
  • CT
  • MRI
  • PET/CT
  • scintigraphy

Published Papers (1 paper)

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Research

19 pages, 2143 KiB  
Article
Neurologic Outcome Comparison between Fetal Open-, Endoscopic- and Neonatal-Intervention Techniques in Spina Bifida Aperta
by Deborah A. Sival, Agnieszka Patuszka, Tomasz Koszutski, Axel Heep and Renate J. Verbeek
Diagnostics 2023, 13(2), 251; https://doi.org/10.3390/diagnostics13020251 - 9 Jan 2023
Cited by 2 | Viewed by 1530
Abstract
Introduction: In spina bifida aperta (SBA), fetal closure of the myelomeningocele (MMC) can have a neuroprotective effect and improve outcomes. In Europe, surgical MMC closure is offered by fetal-open (OSBAR), fetal-endoscopic (FSBAR), and neonatal (NSBAR) surgical techniques. Pediatric neurologists facing the challenging task [...] Read more.
Introduction: In spina bifida aperta (SBA), fetal closure of the myelomeningocele (MMC) can have a neuroprotective effect and improve outcomes. In Europe, surgical MMC closure is offered by fetal-open (OSBAR), fetal-endoscopic (FSBAR), and neonatal (NSBAR) surgical techniques. Pediatric neurologists facing the challenging task of counseling the parents may therefore seek objective outcome comparisons. Until now, such data are hardly available. In SBA, we aimed to compare neurologic outcomes between OSBAR, FSBAR, and NSBAR intervention techniques. Methods: We determined intervention-related complications, neuromuscular integrity, and neurologic outcome parameters after OSBAR (n = 17) and FSBAR (n = 13) interventions by age- and lesion-matched comparisons with NSBAR-controls. Neurological outcome parameters concerned: shunt dependency, segmental alterations in muscle ultrasound density (reflecting neuromuscular integrity), segmental motor-, sensory- and reflex conditions, and the likelihood of intervention-related gain in ambulation. Results: Compared with NSBAR-controls, fetal intervention is associated with improved neuromuscular tissue integrity, segmental neurological outcomes, reduced shunt dependency, and a higher chance of acquiring ambulation in ≈20% of the operated children. Children with MMC-lesions with a cranial border at L3 revealed the most likely intervention-related motor function gain. The outcome comparison between OSBAR versus FSBAR interventions revealed no significant differences. Conclusion: In SBA, OSBAR- and FSBAR-techniques achieved similar neuroprotective results. A randomized controlled trial is helpful in revealing and compare ongoing effects by surgical learning curves. Full article
(This article belongs to the Special Issue State-of-the-Art Research of Pediatric Imaging)
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