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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Artificial Intelligence for Health and Medicine—2nd Edition

edited by

Daniele Giansanti

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1278 | Submission Open

Keywords: artificial intelligence; deep learning; healthcare; image segmentation; disease prediction; monitoring

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Sarcoma Diagnostics: Histopathology, Imaging, and Artificial Intelligence for Precision Management

edited by

Siu Wai Choi

submission deadline 31 Dec 2026 | Viewed by 1197 | Submission Open

Keywords: sarcoma diagnosis and prognosis; machine learning models; genomics in diagnosis; classification and prognosis; novel methods of treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Biochemical Testing Applications in Clinical Diagnosis—2nd Edition

edited by

Donatella Coradduzza

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1070 | Submission Open

Keywords: biochemical testing; clinical diagnosis; biomarkers; point-of-care tests; innovative analytical techniques

(This special issue belongs to the Section Clinical Laboratory Medicine)

Molecular Diagnostics in Cardiovascular Diseases: From Biomarkers to Individualized Medicine

edited by

Priyanka Gokulnath

and

Michail Spanos

submission deadline 31 Dec 2026 | 1 articles | Viewed by 840 | Submission Open

Keywords: molecular diagnostics; cardiovascular diseases; biomarkers; individualized medicine; precision cardiology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advancements in Maternal–Fetal Medicine: 3rd Edition

edited by

Elena Bernad

submission deadline 31 Dec 2026 | Viewed by 799 | Submission Open

Keywords: maternal– fetal medicine; high-risk pregnancy; prenatal diagnostics; psychological distress in pregnancy; anxiety and depression; stress-related disorders; biomarkers; perinatal morbidity and mortality; translational diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Anatomy and Diagnosis in 2026

edited by Ji-Hyun Lee

submission deadline 31 Dec 2026 | Viewed by 725 | Submission Open

Keywords: clinical anatomy; radiological anatomy; applied anatomy; anatomical variations; pathoanatomy; artificial intelligence in anatomy; anatomical research innovation; anatomical education

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

AI-Powered Ophthalmic Diagnostics: From Image Segmentation to Disease Classification

edited by

Yanwu Xu

Weihua Yang

and

Huihui Fang

submission deadline 31 Dec 2026 | 1 articles | Viewed by 711 | Submission Open

Keywords: ophthalmic artificial intelligence; medical image segmentation; disease classification; ocular imaging; deep learning and foundation models; explainable AI (XAI); clinical translation in ophthalmology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Diagnostics and Management of Diseases of the Anterior Segment of the Eye

edited by

Sang Beom Han

submission deadline 31 Dec 2026 | 1 articles | Viewed by 596 | Submission Open

Keywords: anterior segment disorder; cornea; cataract; anterior segment imaging; refractive surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnostic Imaging and Interpretation in Pediatric Radiology

edited by

André Lollert

submission deadline 31 Dec 2026 | 1 articles | Viewed by 499 | Submission Open

Keywords: pediatric radiology; pediatric MRI; pediatric CT; photon-counting CT; pediatric ultrasound; clinico-radiologic diagnostics; rare diseases; quantitative imaging; artificial intelligence; nuclear medicine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Women’s Cardiovascular Health: Advances in Diagnosis, Screening, and Risk Prediction

edited by

Jasjit S. Suri

and

Luca Saba

submission deadline 31 Dec 2026 | 1 articles | Viewed by 453 | Submission Open

Keywords: artificial intelligence; women’ s cardiovascular health; diagnosis; screening; risk prediction

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Emerging Diagnostic Techniques and Therapeutic Strategies in Urological Oncology

edited by

Francesco Chierigo

submission deadline 31 Dec 2026 | Viewed by 354 | Submission Open

Keywords: prostate cancer; screening; biomarkers; genetic testing; imaging; PSMA; artificial intelligence; radical prostatectomy; radiotherapy; hormonal therapies

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Endoscopic Ultrasound: Diagnostic and Therapeutic Innovations

edited by

Andrada Seicean

submission deadline 31 Dec 2026 | Viewed by 280 | Submission Open

Keywords: endoscopic ultrasound (EUS); diagnostic and therapeutic innovations; minimally invasive interventions; EUS-guided tissue acquisition; advanced imaging techniques; multidisciplinary gastroenterology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Deep Learning and Large Models in Ophthalmic Innovations

edited by

Yanwu Xu

Weihua Yang

and Huihui Fang

submission deadline 31 Dec 2026 | Viewed by 274 | Submission Open

Keywords: Artificial Intelligence in ophthalmology; multimodal learning; foundation models; ophthalmic imaging; eye disease diagnosis and treatment

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advanced Ultrasound Techniques in Diagnosis, Second Edition

edited by

Laith Riyadh Sultan

submission deadline 31 Dec 2026 | Viewed by 261 | Submission Open

Keywords: super-resolution imaging; microvascular imaging (MVI); contrast-enhanced ultrasound; AI-guided ultrasound; quantitative analysis; diagnostic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Gastrointestinal Endoscopy: Diagnostic Applications and Safety Evaluation

edited by

Giacomo Emanuele Maria Rizzo

Lucía Guilabert

and Sara Nikolic

submission deadline 31 Dec 2026 | Viewed by 218 | Submission Open

Keywords: endoscopy; endoscopic ultrasound; luminal endoscopy; procedural safety; risk assessment; adverse events; sedation protocols

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Fetal Diagnosis and Therapy: 2nd Edition

edited by Elisa Montaguti and Camilla Dionisi

submission deadline 31 Dec 2026 | Viewed by 210 | Submission Open

Keywords: ultrasound; prenatal diagnosis; NIPT; fetal echocardiography; fetal therapy; fetal MRI

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Endoscopic Diagnosis and Management of Tumors

edited by

Longjun He

submission deadline 31 Dec 2026 | Viewed by 199 | Submission Open

Keywords: endoscopy; tumor diagnosis; endoscopic therapy; endoscopic ultrasound; artificial intelligence; early cancer detection; minimally invasive surgery; precision oncology; molecular imaging; translational research

(This special issue belongs to the Section Biomedical Optics)

Liquid Biopsy and Molecular Diagnostics in Neuro-Oncology

edited by Santiago Cabezas-Camarero and Juan Manuel Sepúlveda-Sánchez

submission deadline 31 Dec 2026 | Viewed by 191 | Submission Open

Keywords: liquid biopsy; biofluids; biomarkers; molecular techniques; gliomas; neuro-oncology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in Medical Image Analysis and Clinical Decision Support

edited by Zahid Ullah and Tahir Mahmood

submission deadline 31 Dec 2026 | Viewed by 188 | Submission Open

Keywords: medical image analysis; deep learning; vision transformers; medical image segmentation; clinical decision support; multimodal learning; explainable AI; continual learning; federated learning; healthcare AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Selected Papers From the 1st International Online Conference on Diagnostics [IOCDi 2026]

edited by

Giorgio Treglia

submission deadline 31 Dec 2026 | Viewed by 173 | Submission Open

Keywords: imaging diagnosis; pathology diagnosis; molecular diagnosis; clinical diagnosis; laboratory medicine; point-of-care diagnosis; artificial intelligence

Recent Advances in Oral and Maxillofacial Surgery: Diagnosis and Management

edited by Kenji Yamagata

submission deadline 31 Dec 2026 | Viewed by 167 | Submission Open

Keywords: oral and maxillofacial surgery; oral diseases; oral cancer; jaw deformity; orthognathic surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis, Prognosis, and Management of the Musculoskeletal System

edited by Massimiliano Leigheb,

Alessandro de Sire

and Cesar de Cesar Netto

submission deadline 31 Dec 2026 | Viewed by 141 | Submission Open

Keywords: musculoskeletal system; diagnostic tools; prognosis; artificial intelligence; augmented reality

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

From Early Diagnosis to Therapy Response: Machine Learning Driven Biomarker Discovery

edited by Wenjie Shi and Rudy Leon De Wilde

submission deadline 31 Dec 2026 | Viewed by 141 | Submission Open

Keywords: machine learning; biomarker discovery; early diagnosis; liquid biopsy; precision medicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Emerging Technologies for Lung Disease Detection and Clinical Assessment

edited by Scott Matson and

Joshua Jay Reicher

submission deadline 31 Dec 2026 | Viewed by 132 | Submission Open

Keywords: medical imaging; artificial intelligence (AI); radiology; machine learning (ML)

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovative Approaches to Vascular Diseases Diagnosis and Management

edited by

Paolo Perini

and

Chiara Martini

submission deadline 31 Dec 2026 | Viewed by 127 | Submission Open

Keywords: vascular imaging; vascular surgery; aortic aneurysm; peripheral arterial disease; venous disease; image-guided therapy; artificial intelligence; 3D printing; medical devices; vascular complications

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Laboratory Diagnosis—2nd Edition

edited by

Giuseppe Lippi

and Camilla Mattiuzzi

submission deadline 31 Dec 2026 | Viewed by 117 | Submission Open

Keywords: laboratory diagnosis; biomarkers; clinical chemistry; laboratory analysis; artificial intelligence

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnostic Advances in Orthodontics and Dentistry

edited by

Antonino Lo Giudice

submission deadline 31 Dec 2026 | Viewed by 113 | Submission Open

Keywords: CBCT facial scanning; oral imaging; orthodontics; digital dentistry; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Cancer Diagnosis and Intervention

edited by Vlad Alexandru Gâta

submission deadline 31 Dec 2026 | Viewed by 109 | Submission Open

Keywords: diagnostic; precision oncology; artificial intelligence; radiomics; molecular biomarkers; interventional oncology; personalized medicine; translational research

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis, Prognosis, and Management of Urinary Disease—2nd Edition

edited by

Nicola Longo

and

Massimiliano Creta

submission deadline 31 Dec 2026 | Viewed by 103 | Submission Open

Keywords: urinary disease; diagnosis; prognosis; kidney disease; prostate disease; malignant diseases like kidney cancer; bladder cancer and prostate cancer

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Lung Monitoring in Critical Care

edited by Lorenzo Ball

submission deadline 31 Dec 2026 | Viewed by 91 | Submission Open

Keywords: lung monitoring; critical care; mechanical ventilation; diagnosis; imaging

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Ultrasound Imaging in Medicine in 2026

edited by

Michael Bachmann Nielsen

submission deadline 31 Dec 2026 | Viewed by 82 | Submission Open

Keywords: 3D ultrasound; blood flow velocity; ultrasonography; contrast-enhanced ultrasound; elasticity imaging; endoscopic ultrasound; intervention

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Perspectives in the Diagnosis of Gastroenterological Diseases

edited by Reena Sidhu

submission deadline 31 Dec 2026 | Viewed by 79 | Submission Open

Keywords: small bowel; bleeding; Crohn’ s disease; endoscopy; coeliac disease; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Accurate Diagnosis and Management of Infectious and Respiratory Diseases

edited by

Marco Goeijenbier

submission deadline 31 Dec 2026 | Viewed by 72 | Submission Open

Keywords: infectious and respiratory diseases; viral and bacterial pathogens; multiplex molecular panels; rapid diagnostic tests; intensive care units

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Precision Diagnosis in Musculoskeletal Disorders: Current and Future Directions

edited by

Yuichi Yoshii

submission deadline 31 Dec 2026 | Viewed by 70 | Submission Open

Keywords: precision diagnosis; musculoskeletal imaging; artificial intelligence; quantitative imaging biomarkers; automated morphological analysis; predictive modeling; 3D patient-specific modeling; digital twin; image-guided diagnosis; personalized musculoskeletal care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovative Diagnostic Strategies for Inherited Metabolic Diseases

edited by Radha Ramachandran

submission deadline 31 Dec 2026 | Viewed by 65 | Submission Open

Keywords: inherited metabolic; diagnostic; prognostic monitoring; personalised genetic functional omics

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Computed Tomography Imaging in Medical Diagnosis, Third Edition

edited by

Fabio Sandomenico

submission deadline 31 Dec 2026 | Viewed by 64 | Submission Open

Keywords: computed tomography; medical diagnosis; imaging; internal organs; bones; soft tissue; blood vessels

(This special issue belongs to the Section Medical Imaging and Theranostics)

Whole-Body PET/CT: From Diagnosis to Prognosis

edited by Ioannis M. Tsougos

submission deadline 31 Dec 2026 | Viewed by 54 | Submission Open

Keywords: whole-body PET/CT; diagnosis; prognosis; human diseases; medical imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Precision Oncology: Integrating Histopathology, Immunohistochemistry, and Molecular Diagnostics

edited by

Tomonori Kawasaki

submission deadline 31 Dec 2026 | Viewed by 53 | Submission Open

Keywords: biomarker; cancer; carcinoma; cytology; diagnosis; fluorescence in situ hybridization; gene; growth factor receptor; histology; hormone receptor; immunohistochemistry; molecular pathology; neoplasm; next-generation sequencing; oncology; pathology; PCR; prognosis; treatment

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnosis and Treatment of Thyroid Cancer

edited by

Chang Myeon Song

submission deadline 31 Dec 2026 | Viewed by 52 | Submission Open

Keywords: thyroid cancer; diagnosis; robotic thyroid surgery; thyroidectomy; molecular diagnostics; minimally invasive surgery; risk stratification; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

A New Era in Diagnosis: From Biomarkers to Artificial Intelligence, 2nd Edition

edited by

Tudor Drugan

and

Daniel Leucuta

submission deadline 31 Dec 2026 | Viewed by 44 | Submission Open

Keywords: biomarkers; diagnosis; personalized medicine; therapeutic strategies; artificial intelligence; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Point-of-Care and At-Home Diagnostics for Infectious Diseases

edited by Gregory J. Tobin and Ke Du

submission deadline 31 Dec 2026 | Viewed by 39 | Submission Open

Keywords: infectious agents; at-home diagnostic; point-of-care diagnostic; pathogen surveillance; digital health; novel detection technologies; low-resource settings

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Clinical Diagnostics and Management in the ICU

edited by

Silvia De Rosa

and Sergio Lassola

submission deadline 31 Dec 2026 | Viewed by 25 | Submission Open

Keywords: intensive care unit; hemodynamic monitoring; acute kidney injury; sepsis and septic shock; clinical diagnostics; predictive biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

From Innovation to Clinical Practice: Anticipating the New Era of AI-Driven Laboratory Medicine

edited by Edda Russo

submission deadline 31 Dec 2026 | Viewed by 5 | Submission Open

Keywords: artificial intelligence (AI); laboratory medicine; data integration; clinical validation; diagnostic strategies

(This special issue belongs to the Section Clinical Laboratory Medicine)

AI‑Driven Innovations in Medical Imaging

edited by

Lulu Wang

submission deadline 30 Jan 2027 | Viewed by 79 | Submission Open

Keywords: medical imaging; artificial intelligence; diagnostic imaging; deep learning; image analysis; clinical decision-making; precision medicine; translational research; trustworthy AI; human– AI collaboration

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Computational Approaches for Medical Diagnosis and Healthcare Settings

edited by

Chenkun Liaw

submission deadline 30 Jan 2027 | Viewed by 62 | Submission Open

Keywords: computer-aided diagnosis; computer-aided healthcare system; overly large healthcare computer system; innovation in health care algorithm

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Deep Learning in Biomedical Image and Signal Processing: Recent Advancements and Applications

edited by Narinder Singh Punn

submission deadline 31 Jan 2027 | 7 articles | Viewed by 10367 | Submission Open

Keywords: deep learning; biomedical image; signal processing; multimodal data fusion; explainable AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advancements in Diagnosis of Colorectal Cancer

edited by

Piero Boraschi

submission deadline 31 Jan 2027 | 1 articles | Viewed by 2644 | Submission Open

Keywords: colorectal cancer; metastatic disease; colorectal liver metastases; chemotherapy; surgery; therapeutic response assessment; biomarkers; tumor regression grading; computed tomography; MRI; PET; intraoperative ultrasound; multidisciplinary management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Insights into the Diagnosis of Pediatric Cholestasis

edited by Paola Francalanci

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1746 | Submission Open

Keywords: extrahepatic cholestasis; intrahepatic cholestasis; biliary atresia; genetic liver disease; inborn errors of metabolism; jaundice; monogenic liver disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Beyond the Tipping Point: Advances in the Diagnosis and Management of Acute-on-Chronic Liver Failure and End-Stage Liver Disease

edited by Jonathan Soldera

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1220 | Submission Open

Keywords: liver cirrhosis; hepatorenal syndrome; acute-on-chronic liver failure; liver transplan-tation; biomarkers; diagnostic imaging; artificial intelligence; inflammation media-tors; prognosis; end-stage liver disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovations in Tuberculosis Diagnostics

edited by

Kanagavel Murugesan

submission deadline 31 Jan 2027 | Viewed by 267 | Submission Open

Keywords: whole genome sequencing (WGS); targeted NGS; computer-aided detection (CAD); digital radiography; exosomes; volatile organic compounds; loop-mediated isothermal amplification (LAMP); NAAT; transcriptomics; proteomics; lateral flow assays

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Displaying special issue 601-650 on page 13 of 14.

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