Yarrowia lipolytica: A Beneficial Yeast as a Biofactory for Biotechnological Applications: 3rd Edition

Dear Colleagues,

Yeasts were used for fermentation processes long before their various properties were discovered and described. Among at least 1500 recognized yeast species, in addition to the most well-known baker’s yeasts, e.g., Saccharomyces cerevisiae, other yeasts also stand out, often characterized by their unique features and capabilities.

Yarrowia lipolytica is one of the most studied “non-conventional” yeast species. The high secretory capacity and the capability of biosynthesis of many important secondary metabolites affect the growing scientific interest and biotechnological importance of this yeast. Y. lipolytica is considered to be non-pathogenic, and additionally, some commercial-scale processes with its participation have been granted GRAS (generally recognized as safe) status by the US Food and Drug Administration (FDA). The major advantages of using Y. lipolytica are its ability to grow and consume of a wide range of substrates, such as alkanes, fatty acids, fats, and oils, as well as some waste substrates, namely, crude glycerol, waste cooking oils, sewage sludge, or olive mill wastewater, with simultaneous biosynthesis of varied metabolites.

This Special Issue will compile the current state-of-the-art research on Y. lipolytica and shed light on the current research directions with the use of this yeast. Potential topics include but are not limited to the following:

• Metabolic engineering of Y. lipolytica;
• The biosynthesis of secondary metabolites, namely enzymes, e.g., lipases or proteases, as well as organic acids, sugar alcohols, flavors, and aromas;
• Whole-cell catalysis;
• Lipid biosynthesis and accumulation;
• Utilization of agri-food waste.

Dr. Bartłomiej Zieniuk
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fermentation is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• Yarrowia lipolytica
• secondary metabolites
• single-cell oils (SCO)
• lipid accumulation
• single-cell proteins (SCP)
• enzymes biosynthesis
• lipases production
• metabolic engineering
• organic acids synthesis
• agri-food waste upgradation
• whole-cell catalysis
• biosynthesis of metal nanoparticles
• bioreactor processes

• Yarrowia lipolytica: A Beneficial Yeast as a Biofactory for Biotechnological Applications in Fermentation (10 articles)
• Yarrowia lipolytica: A Beneficial Yeast as a Biofactory for Biotechnological Applications: 2nd Edition in Fermentation (6 articles)