Innovative Biotechnological Production of Microbial Polysaccharides

A special issue of Fermentation (ISSN 2311-5637). This special issue belongs to the section "Microbial Metabolism, Physiology & Genetics".

Deadline for manuscript submissions: 30 October 2024 | Viewed by 969

Special Issue Editors


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Guest Editor
Ifremer, Laboratoire Ecosystèmes Microbiens et Molécules Marines pour les Biotechnologies EM3B, 44311 Nantes, France
Interests: enzymes to modify polysaccharides; production and molecular biosynthesis of exopolysaccharides; marine microorganisms
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Naples, Italy
Interests: biotechnological applications of microorganisms; fermentative production of biomolecules; microbial polysaccharides
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Microbial polysaccharides synthesized by various microorganisms, including bacteria, yeasts, microalgae, and fungi are complex carbohydrates that exhibit remarkable structural diversity and play a central role in microbial physiology and environmental interactions. Their unique chemical compositions and physical and functional properties make them valuable resources for many industrial applications, as food additives, cosmetic ingredients, pharmaceutical and nutraceutical bioactive compounds, nanocarriers, and biomaterials. Taking advantage of the metabolic capabilities of microbial strains, fermentation processes provide efficient and sustainable ways to produce these polysaccharides with complex structures and unlock the full potential of microbial polysaccharides for industrial and biomedical applications.

This Special Issue is dedicated to exploring advances and cutting-edge challenges in the production of microbial polysaccharides and sharing the latest discoveries, methodologies, and research results. It welcomes all kinds of contributions (original research articles, reviews, and perspectives) that explore various aspects of microbial polysaccharide production, including but not limited to the following:

  • Novel microbial strains and their growth optimization for improving polysaccharide synthesis.
  • Characterization, purification, and functionalization of microbial polysaccharides for industrial applications.
  • Advances in fermentation techniques and bioprocess engineering to improve the production and yield of polysaccharides.
  • Exploration of metabolic pathways and genetic engineering strategies to tailor polysaccharide characteristics.
  • Bioreactor design and scale-up strategies for industrial-scale production.
  • Implementation of AI for optimizations and production control.
  • Innovative sustainable approaches to produce polysaccharides, including raw material selection, waste use, and eco-friendly production practices.

Dr. Christine Delbarre-Ladrat
Dr. Odile Francesca Restaino
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fermentation is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microorganisms
  • carbohydrate polymers
  • bioreactors
  • production optimization
  • sustainability

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Published Papers (1 paper)

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Research

15 pages, 1885 KiB  
Article
Exopolysaccharide Production in Submerged Fermentation of Pleurotus ostreatus under Red and Green Light
by Georgios Bakratsas, Christoforos Tsoumanis, Haralambos Stamatis and Petros Katapodis
Fermentation 2024, 10(6), 313; https://doi.org/10.3390/fermentation10060313 - 13 Jun 2024
Viewed by 752
Abstract
Light controls the developmental, physiological, morphological, and metabolic responses of many fungi. Most fungi respond primarily to blue, red, and green light through their respective photoreceptors. In this study, a screening of different light wavelengths’ effects on submerged Pleurotus ostreatus cultivation in baffled [...] Read more.
Light controls the developmental, physiological, morphological, and metabolic responses of many fungi. Most fungi respond primarily to blue, red, and green light through their respective photoreceptors. In this study, a screening of different light wavelengths’ effects on submerged Pleurotus ostreatus cultivation in baffled flasks was conducted. P. ostreatus growth was not inhibited in all tested conditions, while an equal or higher protein content was observed in comparison with dark conditions. Red and green light favored exopolysaccharide (EPS) production while red and blue light favored intracellular polysaccharide (IPS) production. To focus on EPS production, the effect of red and green light wavelengths on the production of the polysaccharide via submerged cultivation of P. ostreatus LGAM 1123 was tested. Submerged cultivation using red light in baffled flasks resulted in EPS production of 4.1 ± 0.4 g/L and IPS content of 23.1 ± 1.4% of dry weight (dw), while green light resulted in EPS production of 4.1 ± 0.2 g/L and 44.8 ± 5.2% dw IPS content. Similar production levels were achieved in a 3.5 L bioreactor using red light. The EPS produced using red light revealed a polysaccharide with a higher antioxidant activity compared to the polysaccharides produced by green light. In addition, the analysis of the crude polysaccharides has shown differences in biochemical composition. The structural differences and β glucan’s existence in the crude polysaccharides were confirmed by FT-IR analysis. Overall, these polysaccharides could be used in the food industry as they can enhance the functional health-promoting, physicochemical, and sensory properties of food products. Full article
(This article belongs to the Special Issue Innovative Biotechnological Production of Microbial Polysaccharides)
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