Bioactive Peptides: Preparation, Characterization and Properties

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Nutraceuticals, Functional Foods, and Novel Foods".

Deadline for manuscript submissions: closed (10 November 2024) | Viewed by 1012

Special Issue Editors

Beijing Engineering and Technology Research Center of Food Additives, Beijing Technology and Business University, Beijing 100048, China
Interests: antioxidant activity;natural product chemistry;non-alcoholic fatty liver disease;retinal degeneration;apoptosis;polyphenols;ethanol;gut microbiology;electrocardiogram;flavonoids
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Guest Editor
School of Food and Health, Beijing Technology and Business University, Beijing 100048, China
Interests: boactive peptides; protein hydralysates; intestinal flora; probiotics; prebiotics; adhesion

Special Issue Information

Dear Colleagues,

Bioactive peptides are sequences of between 2 and 20 amino acids that can inhibit chronic diseases by modulating and improving physiological functions, so these peptides contribute to maintaining the health of their consumers. Also, bioactive peptides can affect the pro-health or functional properties of food products. The fractionation of a protein hydrolysate revealed a direct relationship between its structure and functional activity. This Special Issue focuses on different factors affecting bioactive peptide structures in terms of their biological and functional properties, such as their antihypertensive, antioxidative, and hypocholesterolemic effects; water-holding capacity; foaming capacity; emulsifying properties; and solubility. Also, this Special Issue focuses on bioactive peptides identified from food protein sources as potential ingredients of health-promoting functional foods.

This planned Special Issue on “Bioactive Peptides: Preparation, Characterization and Properties” will include original studies and review articles focusing on the impact of bioactive peptides, as well as the impact of their functional properties on food processing and human physical performance and health status.

Dr. Chi Zhang
Dr. Liang Zhao
Guest Editors

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Keywords

  • bioactive peptides
  • peptide preparation
  • peptide characterization
  • functional properties
  • peptide identification
  • amino acid sequences
  • intestinal flora
  • chronic disease

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Published Papers (1 paper)

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Research

14 pages, 2763 KiB  
Article
Identification of Protein Hydrolysates from Sesame Meal and In Vivo Study of Their Gastric Mucosal Protective Effects
by Yutong Yuan, Xinyi Wang, Nan Ling, Jingxuan Zhou, Lei Zhao, Baoping Ji, Feng Zhou and Liang Zhao
Foods 2024, 13(24), 4178; https://doi.org/10.3390/foods13244178 - 23 Dec 2024
Viewed by 559
Abstract
This study aimed to investigate the protective effects and defense mechanisms of a sesame meal protein hydrolysate against ethanol-induced acute gastric mucosal injury in mice. The target peptides in the hydrolysate were identified by LC-MS/MS, the activity was predicted by PeptideRanker, and the [...] Read more.
This study aimed to investigate the protective effects and defense mechanisms of a sesame meal protein hydrolysate against ethanol-induced acute gastric mucosal injury in mice. The target peptides in the hydrolysate were identified by LC-MS/MS, the activity was predicted by PeptideRanker, and the KM mice were orally administered distilled water, a sesame peptide, and omeprazole for 24 consecutive days. Acute gastric mucosal injury was then induced in mice with 70% ethanol, except for the CK group. The sesame peptide significantly inhibited the over-accumulation of ALT, AST, MDA, TNF-α, IL-1β, and MPO, while promoting the reduction in GSH, T-AOC, GSSG, and EGF expression. In addition, a Western blotting analysis showed that sesame peptide significantly up-regulated the expression of HO-1 and NQO1 proteins in the Nrf2/Keap1 signaling pathway, and down-regulated Keap1 protein. The defense effect of a sesame peptide on gastric mucosa may be achieved by alleviating the overproduction of lipid peroxides and improving the antioxidant activity. Full article
(This article belongs to the Special Issue Bioactive Peptides: Preparation, Characterization and Properties)
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