Extracts from Edible Plants: Antioxidant, Anti-Inflammatory and Antimicrobial Properties

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Plant Foods".

Deadline for manuscript submissions: 5 February 2026 | Viewed by 1960

Special Issue Editors


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Guest Editor
Durango Institute of Technology (TecNM/Instituto Tecnologico de Durango), Nueva Vizcaya, Durango 34080, Mexico
Interests: functional foods; food engineering; nanotechnology
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Guest Editor
Laboratorio Nacional CONAHCYT de Apoyo a la Evaluación de Productos Bióticos-LaNAEPBi, Unidad de Servicio Tecnológico Nacional de México/Instituto Tecnológico de Ciudad Valles, Ciudad Valles, Mexico
Interests: food science and technology; biotechnology; enzymes
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Special Issue Information

Dear Colleagues,

In recent years, there has been a discernible resurgence of interest in the utilization of edible plant extracts. This resurgence is propelled by a dual force: scientific demand for more natural, sustainable, and health-focused products, and consumer demand for these products. Concurrently, consumers are expressing a renewed interest in the consumption of plants that have historically been part of ancient cultures. They recognize the benefits that have been proven over time and are seeking natural solutions to modern health and wellness challenges. These traditional and often under-explored species are abundant in bioactive compounds, including phenolics, flavonoids, terpenoids, and alkaloids, and have demonstrated significant antioxidant, anti-inflammatory, and antimicrobial properties.

This Special Issue seeks to gather cutting-edge research and reviews that illuminate the potential of these edible plant extracts. Contributions that explore and document the bioactive compound profiles of plant species rooted in ancient dietary traditions, as well as new and emerging species with comparable functional properties, are encouraged. Manuscripts may concentrate on innovative extraction methodologies, the characterization and quantification of phytochemicals, mechanistic insights into the biological activities of these compounds, and the application of plant extracts in improving food quality, extending product shelf life, and promoting human health. Studies addressing sensory attributes, consumer acceptance, regulatory concerns, and sustainability implications are also welcome.

Potential topics include (but not limited to) the following:

  • Rediscovery and functional analysis of ancient or indigenous food plant species;
  • Novel extraction and processing technologies for recovering high-value bioactive compounds;
  • Characterization, quantification, and bioavailability of plant-derived phytochemicals;
  • Mechanistic understanding of antioxidant, anti-inflammatory, and antimicrobial effects;
  • Utilization of plant extracts in product formulation, food preservation, and shelf-life extension;
  • Characterization, quantification, and bioavailability of plant-derived phytochemicals;
  • Novel, "green" extraction and modern processing technologies for recovering high-value bioactive compounds;
  • Characterization through hyphenated analytical techniques, quantification, and bioavailability of plant-derived phytochemicals;
  • Authentication of plant extracts through specific marker compounds by instrumental techniques and novel statistics methods and chemometrics;
  • Safety assessments, regulatory considerations, and consumer perception.

We extend an invitation to researchers to submit original articles, review papers, and short communications that will facilitate a more profound understanding of the opportunities and challenges associated with the extraction of bioactive constituents from both ancient and contemporary edible plant sources. This Special Issue aims to promote the advancement of knowledge in the realm of plant-based research and to encourage the development of next-generation functional foods. It also seeks to honor the valuable wisdom of ancient dietary practices.

Dr. Jose Alberto Gallegos-Infante
Prof. Dr. Pedro Aguilar-Zarate
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Foods is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antioxidant
  • anti-inflammatory
  • antimicrobial
  • edible plants
  • extracts
  • solvents

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Published Papers (3 papers)

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Research

21 pages, 9378 KB  
Article
Integrated Approach for the Optimization of the Sustainable Extraction of Polyphenols from a South American Abundant Edible Plant: Neltuma ruscifolia
by Giuliana S. Seling, Roy C. Rivero, Camila V. Sisi, Verónica M. Busch and M. Pilar Buera
Foods 2025, 14(17), 2927; https://doi.org/10.3390/foods14172927 - 22 Aug 2025
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Abstract
The pods from Neltuma ruscifolia (vinal), an underutilized species, are rich in bioactive functional compounds. However, the extraction procedures to obtain the highest proportion of these compounds, considering sustainability aspects, have not been optimized. This study aimed to optimize and compare [...] Read more.
The pods from Neltuma ruscifolia (vinal), an underutilized species, are rich in bioactive functional compounds. However, the extraction procedures to obtain the highest proportion of these compounds, considering sustainability aspects, have not been optimized. This study aimed to optimize and compare three affordable extraction methods—dynamic maceration (DME), ultrasound-assisted extraction (UE), and microwave-assisted extraction (ME)—to obtain enriched extracts. The effects of temperature, ethanol-to-water ratio in the solvent, extraction time, and frequency (for ME) were evaluated using a Box–Behnken design and response surface methodology to optimize total polyphenolic content (TPC), total flavonoids (TF), and antioxidant capacity (DPPH). Energy consumption and carbon footprints were also assessed, and phenolic compounds in the optimized extracts were identified by HPLC. The ethanol-to-water ratio emerged as the most influential factor, showing synergistic effects with both time and temperature, enabling optimal yields at intermediate ethanol concentrations. Gallic acid, rutin, and theobromine were found to be the most abundant components, followed by cinnamic, caffeic, and chlorogenic acids. Although UE exhibited the lowest energy consumption (0.64 ± 0.03 Wh/mg of TPC), the simple and easily implementable DME—optimized at 40 min, 50 °C, and 42% ethanol—proved to be the most efficient method, combining high extractive performance (TPC 1432 mg GAE/100 g Dw), reduced solvent use, and intermediate energy efficiency (1.84 Wh/mg of TPC). These findings highlight the potential of vinal as a natural source of bioactive ingredients obtained through simple and cost-effective techniques adaptable to small producers while underscoring the value of experimental design in optimizing sustainable extraction technologies and elucidating the interactions between key processing factors. Full article
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20 pages, 2959 KB  
Article
Isolation, Identification, and Antitumor Activities of Glucosinolates and Isothiocyanates in Chinese Cabbage Seeds
by Bei Zhou, Ying Liu, Xi Feng, Qian Liu, Salam A. Ibrahim and Wen Huang
Foods 2025, 14(16), 2808; https://doi.org/10.3390/foods14162808 - 13 Aug 2025
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Abstract
Isothiocyanates (ITCs), which are derivatives of glucosinolates (GSLs) from Brassica plants, have been investigated as anticancer agents. An extensively studied anticancer ITC is sulforaphane, which is found in low amounts in Chinese cabbage. We aim to investigate the types and content of GSLs [...] Read more.
Isothiocyanates (ITCs), which are derivatives of glucosinolates (GSLs) from Brassica plants, have been investigated as anticancer agents. An extensively studied anticancer ITC is sulforaphane, which is found in low amounts in Chinese cabbage. We aim to investigate the types and content of GSLs (precursors of ITCs with anticancer activity) in Chinese cabbage seeds. GSLs from Chinese cabbage seeds were isolated and purified using acidic Al2O3 column chromatography and preparative HPLC. GSL and ITC profiles were further identified using UHPLC-Q-TOF-MS. The antitumor activities of ITC (produced by exogenous enzymatic hydrolysis of GSLs) were evaluated in vitro. Seventeen GSLs and seven ITCs were identified, and the dominant GSLs were gluconapin, glucobrassicanapin, and progoitrin in Chinese cabbage seeds. High-purity gluconapin (>99%) was purified. The ITCs showed synergistic-, dose-, and time-dependent effects on the inhibition of HepG2 cells, and the key ITCs were 3-butenyl ITC, sulforaphane, and 2-phenylethyl ITC. The corresponding parent GSLs were gluconapin, glucoraphanin, and gluconasturtiin, respectively. 3-Butenyl ITC could significantly induce HepG2 cell proliferation (IC50 = 89.44 μg/mL) and apoptosis (p < 0.05). Our results suggested that Chinese cabbage seed could be a valuable source of natural antitumor ingredients. Full article
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24 pages, 1988 KB  
Article
Sweetening with Agavins: Its Impact on Sensory Acceptability, Physicochemical Properties, Phenolic Composition and Nutraceutical Potential of Oak Iced Tea
by Aylín Araiza-Alvarado, Saúl Alberto Álvarez, José Alberto Gallegos-Infante, Jorge Alberto Sánchez-Burgos, Nuria Elizabeth Rocha-Guzmán, Silvia Marina González-Herrera, Martha Rocío Moreno-Jiménez, Rubén Francisco González-Laredo and Verónica Cervantes-Cardoza
Foods 2025, 14(5), 833; https://doi.org/10.3390/foods14050833 - 28 Feb 2025
Viewed by 939
Abstract
Oak infusions enriched with agavins may offer nutraceutical benefits in the development of iced teas. This study evaluated infusions of Quercus sideroxyla and Quercus eduardii leaves formulated with different concentrations of agavins (0, 2, 6, and 10%), analyzing their physicochemical and sensory properties, [...] Read more.
Oak infusions enriched with agavins may offer nutraceutical benefits in the development of iced teas. This study evaluated infusions of Quercus sideroxyla and Quercus eduardii leaves formulated with different concentrations of agavins (0, 2, 6, and 10%), analyzing their physicochemical and sensory properties, chemical stability, and antioxidant capacity. The incorporation of agavins resulted in substantial modifications to physicochemical parameters, including pH, titratable acidity, and soluble solids, thereby enhancing product stability and consistency. Notable distinctions were observed between the two species with respect to their acidogenic response and soluble solid concentration. Interactions between agavins and phenolic compounds, as discerned by UPLC-PDA-ESI-MS/MS and FT-IR, exerted a significant influence on bioactivity of the phenolic constituents, thereby affecting the nutraceutical potential of the infusions. These interactions, facilitated by hydrogen bonds, led to reduction in phenolic acids, such as quinic acid (↓ 43%), and alteration in antioxidant capacity at high concentrations of agavins. The findings underscore the significance of meticulously designing balanced formulations that optimize chemical stability, functionality, and sensory acceptance, thereby ensuring the quality of the final product. Full article
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