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Arsenic Exposure, Metabolism and Health Effects

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Prof. Dr. Hanyong Peng

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State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
Interests: arsenic speciation; DNA nanotechlogies; live cell imaging; molecular diagnostics

Special Issue Information

Dear Colleagues,

Arsenic is classified as a human carcinogen by a number of international organizations. Human epidemiological studies have demonstrated consistent association between elevated arsenic exposure and the prevalence of skin, bladder, and lung cancers, which are the primary sites of human cancer associated with arsenic exposure. More than 100 million people around the world may be at risk. However, there is still a gap between arsenic pollution and its health effect.

The primary objective of this Special Issue is to gain a comprehensive understanding of arsenic exposure, metabolism and health effects. We hypothesize that (1) arsenic distribution in the enviroment increases the risk of exposure, including water, soil, air, plants, etc.; (2) metabolism of arsenic increases its toxicity, including methylation, thiolation, etc.; (3) interaction between arsenic and biomolecules alters the biological funcution in living organisms such as co-carcinogens or inhibitors by augmenting the carcinogenic potential of genotoxic agents, inhibiting DNA repair enzymes, etc. Previous works support these hypotheses. We aim to address the current knowledge gaps of arsenic research in this Special Issue.

We will accept manuscripts related to various disciplines, including arsenic exposure assessment, arsenic speciation methodology, arsenic metabolism pathway, arsenic toxicity, arsenic monitoring devices, arsenic health-impact assessment, etc. Research papers, reviews, case reports, conference papers, and other manuscript types are all welcome.

Prof. Dr. Hanyong Peng
Guest Editor

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Keywords

arsenic
arsenic speciation
arsenic toxicity
arsenic carcinogenicity
arsenic adsorption
ICP-MS
ESI–MS

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19 pages, 1180 KiB

Open AccessArticle

Arsenic Elevated Groundwater Irrigation: Farmers’ Perception of Rice and Vegetable Contamination in a Naturally Arsenic Endemic Area

by Md Rokonuzzaman, Zhihong Ye, Chuan Wu and Wai-Chin Li

Int. J. Environ. Res. Public Health 2023, 20(6), 4989; https://doi.org/10.3390/ijerph20064989 - 12 Mar 2023

Cited by 1 | Viewed by 1336

Abstract

Arsenic (As) in groundwater and its accumulation in agricultural produces has caused serious threats to human health. The majority of current research on As mainly focuses on the technical aspects while bypassing the social perspectives. Farmers are the prime stakeholders as well as executors of agricultural strategies, and their adaptation largely depends on how they perceive the risk for which a mitigation strategy is proposed. This study aims to explore how rice and vegetable farmers perceive As accumulation in their rice and vegetables as well as explore current crop- and body-loading status, the subsequent health consequences of As, and alleviation possibilities with mitigation strategies and to investigate if there is an association between their socioeconomic status and their level of perception. Results reveal that one-fourth of the farmers gave a positive message regarding the As-contamination scenario in rice and vegetables. Although 10 farmers’ socioeconomic characteristics were positively significant, distinctive emphasis should be given to five predictor variables explaining 88% variances: knowledge, direct participation in farming, information sources used, participant education, and organizational participation. Path analysis depicts that direct participation in farming presents the highest positive total effect (0.855) and direct effect (0.503), whereas information sources show the highest positive indirect effect (0.624). The mean As content in all five locations was statistically significant at the 5%, 5%, 0.1%, 1%, and 1% probability levels in scalp hairs, rice, vegetables, soils, and irrigation water, respectively. The first principal component (PC1) explains 92.5% of the variation. Significant variations were primarily explained by As levels in irrigation water, rice grain, and soil. Farmers’ perception is far behind the actual field status of As level and its transfer. Therefore, intensified priorities should be administered on the farmers’ characteristics contributing to variances in perception. The findings can be utilized for policy formulation in all As-endemic nations. More multidisciplinary research can be undertaken on farmers’ attitude towards adopting As-mitigation techniques, with a focus on the socioeconomic position found to influence farmers’ perceptions. Full article

(This article belongs to the Special Issue Arsenic Exposure, Metabolism and Health Effects)

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