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Advanced Research in Cardiovascular Disease

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Behavior, Chronic Disease and Health Promotion".

Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 2891

Special Issue Editor


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Guest Editor
Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Jacksonville, FL 32224, USA
Interests: cardiovascular disease and health; cerebrovascular disease; dementia; cardiomyopathy; heart failure; vascular disease and health; stress

Special Issue Information

Dear Colleagues,

I am a research associate at Mayo Clinic and My long-term research goals involve acquiring comprehensive knowledge and understanding of the critical molecular mechanism and the signaling cascades involved in cardiovascular and cerebrovascular diseases, particularly in cardiac regenerations, Myocardial infarctions (MI), and cerebral strokes in the elderly. I am one of the key scientists in our cardiovascular and neurovascular program that directly helps several cardiovascular projects related to cardiac fibrosis and sudden cardiac arrest. My research is also involved in the basic understanding of vascular dementia and Alzheimer’s Disease (AD) connected to the role of the cerebrovascular component to the brain that leads to a new therapy for unmade clinical needs for Alzheimer’s patients.

I am also one of the leading experts in Zebrafish facilities that help genetic editing important pathogenesis in different diseases, including cancer, cardiovascular and neurovascular. My critical contributions to the advancement of targeted anti-cancer drug delivery and record of accomplishments clearly distinguish me from other researchers in his field. Academic and industrial communities have recognized my original and significant contributions as an extraordinary scientist.

Dr. Angom Ramcharan Singh
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiovascular disease and health
  • cerebrovascular disease
  • dementia
  • cardiomyopathy
  • heart failure
  • vascular disease and health
  • stress

Published Papers (1 paper)

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Research

8 pages, 872 KiB  
Article
PEEP-ZEEP Compared with Bag Squeezing and Chest Compression in Mechanically Ventilated Cardiac Patients: Randomized Crossover Clinical Trial
by Taís Flores de Oliveira, Vinicius Serra Peringer, Luiz Alberto Forgiarini Junior and Bruna Eibel
Int. J. Environ. Res. Public Health 2023, 20(4), 2824; https://doi.org/10.3390/ijerph20042824 - 5 Feb 2023
Cited by 4 | Viewed by 1878
Abstract
Background and Objectives: Perform the bag squeezing and PEEP-ZEEP techniques associated with manual chest compression in mechanically ventilated cardiac patients in order to observe their effectiveness in the removal of pulmonary secretions and safety from a hemodynamic and ventilatory point of view. [...] Read more.
Background and Objectives: Perform the bag squeezing and PEEP-ZEEP techniques associated with manual chest compression in mechanically ventilated cardiac patients in order to observe their effectiveness in the removal of pulmonary secretions and safety from a hemodynamic and ventilatory point of view. Methods: This is a randomized crossover clinical trial developed in a hospital in southern Brazil. We included hemodynamically stable male and female patients aged over 18 years who used invasive mechanical ventilation for at least 48 h. The control group was established for the bag-squeezing technique and the intervention group for the PEEP-ZEEP maneuver, both associated with manual chest compression. Tracheal aspiration was performed 2 h before in order to match the groups in relation to the volume of secretion, and also immediately at the end of the techniques in order to measure the amount of secretion collected. Results: The sample had 36 individuals with a mean age of 70.3 years, 21% of the patients were male, and the majority (10.4%) were hospitalized for ischemic heart disease. DBP (p = 0.024), MAP (p = 0.004) and RR (p = 0.041) showed a significant difference in the post-moment in both groups. There was a significant difference in the reduction of peak pressure values (p = 0.011), in the moment after performing the techniques, and also in the Cdyn (p = 0.004) in the control group versus moment. Conclusions: Both maneuvers are safe in terms of hemodynamics and ventilatory mechanics, in addition to being capable of favoring airway clearance through secretion removal, and they can be used in routine physiotherapeutic care. Full article
(This article belongs to the Special Issue Advanced Research in Cardiovascular Disease)
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